165529-01-1

Upstream product

• 160952-47-6 t-butyl 3-bromo-4-[[(2-phenylethyl)amino]methyl]-benzoate 
• 165528-99-4 3-bromo-4-bromomethyl-benzoic acid tert-butyl ester 
• 160952-57-8 3-bromo-4-methylbenzoic acid tert-butyl ester 
• 64-04-0 phenethylamine 
• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 617-52-7 Dimethyl itakonate 
• 160952-48-7 t-butyl 3-bromo-4-[[[N-(2-phenylethyl)-N-t-butoxycarbonyl]amino]methyl]benzoate 

Downstream Products

• 165529-02-2 methyl 3-methoxycarbonyl-4-[5-(t-butoxycarbonyl)-2-[[[N-(2-phenylethyl)-N-t-butoxycarbonyl]amino]methyl]-phenyl]butanoate 
• 160952-52-3 (+/-)-7-carboxy-3-oxo-2-(2-phenylethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate 
• 165529-03-3 methyl 3-methoxycarbonyl-4-[5-carboxy-2-[[N-(2-phenylethyl)amino]methyl]phenyl]butanoate 
• 171049-49-3 methyl (R,S)-7-[[[4-(aminoiminomethyl)phenyl]methylamino]-carbonyl]-2,3,4,5-tetrahydro-3-oxo-2-(2-phenylethyl)-1H-2-benzazepine-4-acetate 
• 160952-53-4 {7-[(4-{Amino-[(E)-benzyloxycarbonylimino]-methyl}-phenyl)-methyl-carbamoyl]-3-oxo-2-phenethyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl}-acetic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of a 2-benzazepine analog of a potent, nonpeptide GPIIb/IIIa antagonist

The preparation of the 2-benzazepine derivative 3 as an analog of the potent, nonpeplide GPIIb/IIIa antagonist 2 is reported. The synthetic route employs as key steps a Heck arylation of dimethyl itaconate and a selective cyclization to form the aryl-fuse