165657-74-9 Usage
Description
(R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE, with the molecular formula C7H12O2I, is a dioxolane derivative featuring a six-membered heterocyclic ring with two oxygen atoms. (R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE has a chiral center, denoted by the (R) configuration, and includes an iodine atom and an ethyl group in its structure. It is a versatile chemical entity utilized in various applications across different industries.
Uses
Used in Organic Synthesis:
(R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE is used as a reagent in organic synthesis for its ability to facilitate the formation of complex organic compounds. Its unique structure with a chiral center and functional groups makes it a valuable component in creating a wide range of molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE is used as an intermediate in the production of various drugs. Its structural properties allow it to be a key building block in the synthesis of medicinal compounds, contributing to the development of new and improved pharmaceuticals.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, (R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE serves as an intermediate for the synthesis of different agrochemicals. Its role in creating complex molecules aids in the development of more effective and targeted products for agricultural applications.
Used in Research and Development:
(R)-4-(2-IODO-ETHYL)-2,2-DIMETHYL-[1,3]DIOXOLANE is also utilized in research and development settings as a building block for the synthesis of more complex organic compounds. Its unique structure and properties make it an attractive candidate for exploring new chemical reactions and creating novel molecules with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 165657-74-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,6,5 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 165657-74:
(8*1)+(7*6)+(6*5)+(5*6)+(4*5)+(3*7)+(2*7)+(1*4)=169
169 % 10 = 9
So 165657-74-9 is a valid CAS Registry Number.
165657-74-9Relevant articles and documents
METHODS FOR SYNTHESIS OF RESOLVINS
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Paragraph 0084, (2019/04/10)
The present invention provides methods for chemical synthesis of a resolvin compound such as resolvin E1 (RvE1), or a pharmaceutically acceptable salt thereof; and chemically stable formulations of said compound.
Cobalt versus Osmium: Control of Both trans and cis Selectivity in Construction of the EFG Rings of Pectenotoxin 4
Roushanbakhti, Ahria,Liu, Yifan,Winship, Paul C. M.,Tucker, Michael J.,Akhtar, Wasim M.,Walter, Daryl S.,Wrigley, Gail,Donohoe, Timothy J.
supporting information, p. 14883 - 14887 (2017/10/24)
Catalytic oxidative cyclisation reactions have been employed for the synthesis of the E and F rings of the complex natural product target pectenotoxin 4. The choice of metal catalyst (cobalt- or osmium-based) allowed for the formation of THF rings with either trans or cis stereoselectivity. Fragment union using a modified Julia reaction then enabled the synthesis of an advanced synthetic intermediate containing the EF and G rings of the target.
The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside
Kumar, Chidambaram Ramesh,Tsai, Chi-Hui,Chao, Yu-Sheng,Lee, Jinq-Chyi
experimental part, p. 8696 - 8703 (2011/10/04)
The first total synthesis of cytopiloyne 1, a novel bioactive polyacetylenic glucoside isolated from the extract of Bidens pilosa, is described. The structure of cytopiloyne was determined to be 2-β-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne by using various spectroscopic methods, but the chirality of the polyyne moiety was unknown. Herein, the convergent synthesis of two diastereomers of cytopiloyne by starting from commercially available 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-diozolane is described. The synthetic sequence involved two key steps: stereoselective glycosylation of the glucosyl trichloroacetimidate with 1-[(4-methoxybenzyl)oxy] hex-5-yn-2-ol to give the desired β-glycoside and the construction of the glucosyl tetrayne skeleton by using a palladium/silver-catalyzed cross-coupling reaction to form the alkyne-alkyne bond, the first such use of this reaction. Comparison between the observed and published characterization data showed the 2R isomer to be the natural product cytopiloyne.
