16582-87-9

Basic information

• Product Name: 1,2,3,4-tetrafluoro-5,6-dinitrobenzene
• CAS NO: 16582-87-9
• Molecular Weight: 240.071
• Mol File: 16582-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,3,4-tetrafluoro-5,6-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-tetrafluoro-5,6-dinitrobenzene(16582-87-9)
• EPA Substance Registry System: 1,2,3,4-tetrafluoro-5,6-dinitrobenzene(16582-87-9)

Safety Data

• Hazardous Substances Data: 16582-87-9(Hazardous Substances Data)

Usage

Usage

Production of pharmaceuticals
Production of dyes
Production of pesticides

Reactivity

Highly reactive

Toxicity

Toxic

Health Hazards

Skin irritation
Eye irritation
Respiratory system irritation

Environmental Impact

Potential environmental pollutant

Environmental Behavior

Can undergo oxidation
Can undergo degradation
Formation of harmful by-products

Regulatory Status

Strictly regulated use and handling

Safety Precautions

Proper safety precautions must be taken when working with this compound

Upstream product

• 6157-98-8 2,3,4,5-tetrafluoro-6-nitroaniline 
• 407-25-0 trifluoroacetic anhydride 
• 880-78-4 pentafluoronitrobenzen 
• 16582-88-0 N-(2,3,4,5-tetrafluorophenyl)acetamide 
• 16582-89-1 2.3.4.5-Tetrafluor-6-nitro-acetanilid 

Relevant articles and documents

Polyhalogenonitrobenzenes and derived compounds: Part 5. Improved preparations of 1,2,3,4-tetrafluoro-5,6-dinitrobenzene and 3,4,5,6-tetrafluoro-1,2-phenylenediamine, and the use of the latter for the synthesis of tetrafluorobenzheterocycles

The preparation of 2,3,4,5-tetrafluoro-6-nitroaniline (3) by amination of pentafluoronitrobenzene has been speeded up, scaled up and the yield increased by controlling the reaction by TLC monitoring and using 'dry column' chromatography. Compound (3) was readily converted to 1,2,3,4-tetrafluoro-5,6-dinitrobenzene (2) by peroxytrifluoroacetic acid and to 3,4,5,6-tetrafluoro-1,2-phenylenediamine (1) by SnCl2/HCl, Compound (1) was shown to be a versatile intermediate for the synthesis of tetrafluoro-benzimidazoles, -triazoles and -quinoxalines. The fungicidal activity of the latter are reported here.