165960-92-9

Upstream product

• 165960-90-7 (-)-(2S,3S,6R,7R,10S,11S)-2,3:10,11-Diepoxy-6,7-O-isopropylidene-1,12-O-bis(4-nitrobenzoyl)-1,6,7,12-tetrahydroxydodecane 
• 122-04-3 4-nitro-benzoyl chloride 
• 124-63-0 methanesulfonyl chloride 
• 204637-90-1 (-)-(2S,3R,6R,7R,10R,11S)-1,12-O-Bis(4-nitrobenzoyl)-3,6:7,10-diepoxy-1,2,11,12-tetrahydroxydodecane 

Downstream Products

• 1026914-62-4 Benzoic acid (S)-4-{(2R,13R)-2,13-bis-methoxymethoxy-13-[(2R,5R,2'R,5'R)-5'-((S)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-tridecyl}-2-methyl-5-oxo-tetrahydro-furan-3-yl ester 
• 1026813-71-7 Benzoic acid (S)-4-{(2R,13S)-2,13-bis-methoxymethoxy-13-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-tridecyl}-2-methyl-5-oxo-tetrahydro-furan-3-yl ester 
• 165961-06-8 Toluene-4-sulfonic acid (S)-2-{(2R,5R,2'R,5'R)-5'-[(1R,12R)-15-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-12-methoxymethoxy-pentadecyl]-octahydro-[2,2']bifuranyl-5-yl}-2-hydroxy-ethyl ester 
• 165961-18-2 tert-Butyl-{(S)-2-methoxymethoxy-2-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxy}-diphenyl-silane 
• 165961-17-1 (+)-(2S,3R,6R,7R,10R,11R)-1-O-(tert-Butyldiphenylsilyl)-2-O-(methoxymethyl)-3,6:7,10-diepoxy-1,2,11-trihydroxyhenicosane 
• 165961-20-6 Toluene-4-sulfonic acid (S)-2-methoxymethoxy-2-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-ethyl ester 
• 165961-21-7 Toluene-4-sulfonic acid (S)-2-hydroxy-2-[(2R,5R,2'R,5'R)-5'-((R)-1-hydroxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-ethyl ester 
• 165961-14-8 C₂₉H₃₄N₂O₁₅S 

Relevant academic research and scientific papers

Novel acyclic ligands for metal cations based on the adjacent bistetrahydrofuran as analogs of natural Annonaceous acetogenins

The acrylic ligands with an adjacent bistetrahydrofuran (THF) skeleton have been synthesized as analogs of bullatacin, a representative natural product in a family of Annonaceous acetogenins, and their binding properties towards metal cations have been in

The First Total Synthesis of (+)-Bullatacin, a Potent Antitumor Annonaceous Acetogenin, and (+)-(15,24)-bisepi-Bullatacin

This paper reports the first total synthesis of the natural product (+)-bullatacin (1), a representative of potent antitumor Annonaceous acetogenins, as well as a stereoisomer (+)-(15,24)-bisepi-bullatacin (2).In this synthesis, a new, efficient method has been developed to introduce the γ-lactone into the bistetrahydrofuran skeleton through in situ alkylation of epoxide 4 by the α-sulfonyl carbanion of phenylsulfone 5.The methylated γ-lactone was successfully synthesized by a sequence of reactions comprising an aldol reaction, an acidic lactonization, and elimination under mild, basic condition.