16606-46-5

Basic information

• Product Name: 1,2-dihydro-1-phenylnaphthalene
• Synonyms: 1,2-dihydro-1-phenylnaphthalene;1-Phenyl-1,2-dihydronaphthalene;Einecs 240-658-8
• CAS NO: 16606-46-5
• Molecular Formula: C₁₆H₁₄
• Molecular Weight: 206.28236
• EINECS: 240-658-8
• Mol File: 16606-46-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 319.3°Cat760mmHg
• Flash Point: 153°C
• Appearance: /
• Density: 1.064g/cm³
• Vapor Pressure: 0.000639mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 1,2-dihydro-1-phenylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dihydro-1-phenylnaphthalene(16606-46-5)
• EPA Substance Registry System: 1,2-dihydro-1-phenylnaphthalene(16606-46-5)

Safety Data

• Hazardous Substances Data: 16606-46-5(Hazardous Substances Data)

Usage

Chemical structure

Polycyclic aromatic hydrocarbon with a naphthalene core and a phenyl group attached to one of the carbon atoms.

Applications

a. Production of dyes
b. Production of pharmaceuticals
c. Synthesis of various organic compounds

Physical properties

a. Flammable liquid
b. High melting point

Chemical properties

a. Exhibits aromatic properties
b. Exhibits aliphatic properties

Safety concerns

a. Potential health hazards if not used properly
b. Importance of handling with care

InChI:InChI=1/C16H14/c1-2-7-13(8-3-1)16-12-6-10-14-9-4-5-11-15(14)16/h1-11,16H,12H2

Upstream product

• 100-42-5 styrene 
• 147506-92-1 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl 
• 79628-38-9 bis(1,2,3,4-tetrahydro-4-phenyl-1,1-naphthyl)diazene 
• 7469-40-1 1-phenyl-3,4-dihydronaphthalene 
• 591-50-4 iodobenzene 
• 447-53-0 1,2-Dihydronaphthalene 
• 201345-00-8 (E)-1-benzylidene-2-phenylcyclopropane 
• 1187323-16-5 cis-(2R,4R)-4-phenyltetral-2-yl tosylate 
• 124-40-3 dimethyl amine 
• 62708-42-3 o-allylbenzaldehyde 
• 91-20-3 naphthalene 
• 71-43-2 benzene 
• 100-58-3 phenylmagnesium bromide 
• 14578-67-7 4,4-diphenylbutanoic acid 

Downstream Products

• 605-02-7 1-phenylnaphthalene 
• 3018-20-0 1-phenyl-1,2,3,4-tetrahydronaphthalene 
• 13387-49-0 1-phenyl-1,4-dihydronaphthalene 
• 7469-40-1 1-phenyl-3,4-dihydronaphthalene 
• 132884-11-8 1-(o-benzylphenyl)allene 
• 85803-90-3 exo-4-phenylbenzobicyclo<3.1.0>hex-2-ene 
• 132884-12-9 (1S,αS;1R,αR)-1-(α-methoxybenzyl)indan 
• 14090-18-7 cis-dibenzobicyclo<3.3.0>octa-2,7-diene 
• 85803-90-3 endo-4-phenylbenzobicyclo<3.1.0>hex-2-ene 
• 132884-12-9 (1R,αS;1S,αR)-1-(α-methoxybenzyl)indan 
• 83810-61-1 4-Phenyl-3,4-dihydro-naphthalene-1-carboxylic acid methyl ester 
• 83810-59-7 2-Oxo-4-phenyl-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid methyl ester 
• 78604-95-2 1,3,5-Triphenyl-4,5-dihydro-1H-benzo[g]indazole 
• 51751-10-1 4-Phenyl-1,2,3,4-tetrahydro-1-naphthol 

Relevant articles and documents

Transition-Metal-Free Synthesis of Polyfunctional Triarylmethanes and 1,1-Diarylalkanes by Sequential Cross-Coupling of Benzal Diacetates with Organozinc Reagents

A variety of functionalized triarylmethane and 1,1-diarylalkane derivatives were prepared via a transition-metal-free, one-pot and two-step procedure, involving the reaction of various benzal diacetates with organozinc reagents. A sequential cross-coupling is enabled by changing the solvent from THF to toluene, and a two-step SN1-type mechanism was proposed and evidenced by experimental studies. The synthetic utility of the method is further demonstrated by the synthesis of several biologically relevant molecules, such as an anti-tuberculosis agent, an anti-breast cancer agent, a precursor of a sphingosine-1-phosphate (S1P) receptor modulator, and a FLAP inhibitor.

Photoredox-Catalyzed Dimerization of Arylalkenes via an Oxidative [4+2] Cycloaddition Sequence: Synthesis of Naphthalene Derivatives

We report a radical cation [4+2] annulation of arylalkenes to afford naphthalene derivatives using an organic photosensitizer (9-mesityl-10-methylacridinium perchlorate) under visible light photocatalysis. In the presence of oxygen (in the air), the oxidative dimerization/intramolecular [4+2] cycloaddition of two alkene molecules provides 3,4-dihydronaphthalen-1(2H)-ones in good to high yields. Under a nitrogen atmosphere, (dihydro)naphthalenes were attained in moderate to excellent yields by using Selectfluor as the oxidant. The transformation proceeds via a tandem dimeric electrophilic addition/Friedel–Crafts cyclization/radical coupling/elimination sequence. This approach represents a mild and straightforward assembly of the naphthalene skeleton using a visible light photocatalytic cascade strategy. (Figure presented.).