16611-56-6Relevant academic research and scientific papers
The Preparation of Sodium 4-Amino-3-nitrobenzenesulfonate and Some Related Compounds
Rosevear, Judi,Wilshire, John F. K.
, p. 1727 - 1732 (2007/10/02)
The sodium salt of 4-amino-3-nitrobenzenesulfonic acid (o-nitroaniline-p-sulfonic acid) has been prepared by the action of dilute sodium hydroxide solution on ethyl carbamate.Central to this synthesis is the finding that the N-ethoxycarbonyl group, when located ortho to a nitro group (but not to a bromo group), is readily removed by dilute sodium hydroxide solution.
REACTION OF 2,4-DISUBSTITUTED CHLOROBENZENES WITH 3-ALKYLAMINO- AND 3-DIALKYLAMINOPROPIONITRILES
Plakidin, Val. L.,Vostrova, V. N.
, p. 295 - 303 (2007/10/02)
The reaction of 2,4-disubstituted chlorobenzenes with 3-dialkylaminopropionitriles at 65-170 deg C leads to the formation of 2,4-disubstituted N,N-dialkylanilines, and the reaction with 3-alkylaminopropionitriles at 20-130 deg C leads to the formation of 2,4-disubstituted N-alkyl-N-β-cyanoethylanilines.In addition, in the latter case at high temperature (130 deg C) the cyanoethyl group is removed from the substituted N-alkyl-N-β-cyanoethylaniline with the formation of the 2,4-disubstituted N-alkylaniline.
