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2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is a boronic acid compound characterized by the chemical formula C8H8BF3O4. It is a white to off-white solid that is soluble in organic solvents such as dichloromethane and tetrahydrofuran. This versatile reagent is widely used in organic synthesis and serves as a building block in the production of pharmaceuticals and agrochemicals. Its potent cross-coupling capabilities, particularly in the Suzuki-Miyaura coupling reaction, make it an essential tool in the field of chemical synthesis, contributing to the development of new compounds with potential therapeutic and commercial applications.

355836-10-1

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355836-10-1 Usage

Uses

Used in Organic Synthesis:
2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is used as a reagent in organic synthesis for its ability to form carbon-carbon bonds, which is crucial for the construction of complex organic molecules. Its reactivity and stability make it a valuable component in the synthesis of various organic compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is used as a building block for the development of new drugs. Its incorporation into molecular structures can enhance the pharmacological properties of drug candidates, contributing to the discovery of novel therapeutic agents.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is utilized as a key component in the synthesis of pesticides and other agrochemicals. Its role in creating new molecules with improved efficacy and selectivity is vital for the advancement of crop protection strategies.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is employed as a potent cross-coupling reagent in the Suzuki-Miyaura reaction, a widely used method for the formation of carbon-carbon bonds. Its application in this reaction facilitates the synthesis of a broad range of organic compounds, including those with potential applications in materials science, medicinal chemistry, and other fields.
Overall, 2-Methoxy-4-(trifluoromethoxy)phenylboronic acid's versatility and reactivity make it an indispensable asset in the fields of organic synthesis, pharmaceutical development, and agrochemical production, driving innovation and the creation of new compounds with significant therapeutic and commercial potential.

Check Digit Verification of cas no

The CAS Registry Mumber 355836-10-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,5,8,3 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 355836-10:
(8*3)+(7*5)+(6*5)+(5*8)+(4*3)+(3*6)+(2*1)+(1*0)=161
161 % 10 = 1
So 355836-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H8BF3O4/c1-15-7-4-5(16-8(10,11)12)2-3-6(7)9(13)14/h2-4,13-14H,1H3

355836-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-methoxy-4-(trifluoromethoxy)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names AM934

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:355836-10-1 SDS

355836-10-1Relevant academic research and scientific papers

Selective sodium channel regulator, preparation and application thereof

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Paragraph 0083; 0085; 0089; 0090; 0091, (2021/07/01)

The invention provides a compound as a selective sodium channel regulator, a synthesis method and a use method thereof, and particularly provides a compound as shown in a formula (I), a preparation method of the compound and application of the compound as the selective sodium channel regulator. The compounds exhibit excellent activity as sodium channel modulators.

Selective sodium channel regulator as well as preparation and application thereof

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Paragraph 0094-0095; 0099-0101, (2021/02/10)

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

Selective sodium channel regulator as well as preparation and application thereof

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Paragraph 0088; 0090; 0103-0105, (2021/02/10)

The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.

HETEROARYL FUSED PYRIDINES, PYRAZINES AND PYRIMIDINES AS CRF1 RECEPTOR LIGANDS

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Page/Page column 57-58, (2010/02/11)

Substituted heteroaryl fused pyridine, pyrazine, and pyrimidine compounds that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxi

5-Aryl-pyrazolo[4,3-d]pyrimidines, pyridines, and pyrazines and related compounds

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Page/Page column 30, (2010/02/11)

5-aryl-Pyrazolo[4,3-d]pyrimidines, 6-aryl-Pyrazolo[3,4-d]pyrimidines and related compounds, as well as other chemically related compounds, that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a n

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