355836-10-1

Basic information

• Product Name: 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID
• Synonyms: 2-METHOXY-4-(TRIFLUOROMETHOXY)BENZENEBORONIC ACID;2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID;4-(DIFLUOROMETHOXY)-2-METHOXYPHENYL]BORONIC ACID
• CAS NO: 355836-10-1
• Molecular Formula: C₈H₈BF₃O₄
• Molecular Weight: 235.95
• Product Categories: Boronate Ester;Boronic Acid;Potassium Trifluoroborate
• Mol File: 355836-10-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 312.9 °C at 760 mmHg
• Flash Point: 143.1 °C
• Appearance: /
• Density: 1.406 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID(355836-10-1)
• EPA Substance Registry System: 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID(355836-10-1)

Safety Data

• Hazardous Substances Data: 355836-10-1(Hazardous Substances Data)

Usage

General Description

2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is a boronic acid compound with the chemical formula C8H8BF3O4. It is used as a reagent in organic synthesis and as a building block in the production of pharmaceuticals and agrochemicals. 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID is a potent and versatile cross-coupling reagent and is commonly used in the Suzuki-Miyaura coupling reaction. It is a white to off-white solid that is soluble in organic solvents such as dichloromethane and tetrahydrofuran. 2-Methoxy-4-(trifluoromethoxy)phenylboronic acid is an important tool in the field of chemical synthesis and plays a crucial role in the development of new compounds with potential therapeutic and commercial applications.

InChI:InChI=1/C8H8BF3O4/c1-15-7-4-5(16-8(10,11)12)2-3-6(7)9(13)14/h2-4,13-14H,1H3

Upstream product

• 848360-85-0 1-bromo-2-methoxy-4-(trifluoromethoxy)benzene 
• 121-43-7 Trimethyl borate 
• 5419-55-6 Triisopropyl borate 
• 827-99-6 3-(trifluoromethoxy)phenol 
• 205371-26-2 2-bromo-5-(trifluoromethyloxy)phenol 
• 7732-18-5 water 

Downstream Products

• 477597-09-4 2,5-diethyl-3-(1-ethyl-propoxy)-6-(2-methoxy-4-trifluoromethoxy-phenyl)-pyridine 
• 848361-08-0 C₂₁H₂₅BrF₃N₃O₂ 
• 166312-49-8 2-methoxy-4-(trifluoromethoxy)phenol 

Relevant articles and documents

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