166322-69-6Relevant academic research and scientific papers
Synthetic study for two 2H-chromenic acids, 8-chlorocannabiorcichromenic acid and mycochromenic acid
Yamaguchi, Seiji,Nedachi, Masahiro,Maekawa, Mikiko,Murayama, Yohei,Miyazawa, Masahiro,Hirai, Yoshiro
, p. 29 - 41 (2007/10/03)
Two 2H-chromenes having a fully substituted benzene ring, 8-chlorocannabioreichromene (1) and mycochromenic acid (2), were synthesized by a condensation of salicylaldehydes with isopropylidenemalonate or the thermal cyclization of corresponding propargyl ethers.
An improved synthesis of 5,7-dimethoxy-4-methyl-phthalide, a key intermediate in the synthesis of mycophenolic acid
Makara, Gergely M.,Klubek, Kevin,Anderson, Wayne K.
, p. 1935 - 1942 (2007/10/03)
An efficient synthetic pathway is described for 5,7-dimethoxy-4-methylphthalide, a key intermediate in the synthesis of mycophenolic acid and its analogues. The procedure starts from methyl 3,5-dimethoxybenzoate and involves five simple steps to give phth
