166329-43-7

Basic information

• Product Name: TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE
• Synonyms: TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE;2-Boc-aminobenzyl bromide;N-tert-butoxycarbonyl-2-bromomethylaniline
• CAS NO: 166329-43-7
• Molecular Formula: C₁₂H₁₆BrNO₂
• Molecular Weight: 286.16
• Mol File: 166329-43-7.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE(166329-43-7)
• EPA Substance Registry System: TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE(166329-43-7)

Safety Data

• Hazardous Substances Data: 166329-43-7(Hazardous Substances Data)

Usage

General Description

"TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE" is a chemical compound that contains a tert-butyl group, a phenyl group, and a carbamate functional group. The presence of the bromomethyl group makes it a brominated compound, which can have various applications in organic synthesis and chemical reactions. The tert-butyl group provides steric hindrance, which can influence the reactivity and selectivity of the compound in certain reactions. The carbamate functional group indicates the presence of a carbonyl group linked to an amino group, which can participate in hydrogen bonding and other intermolecular interactions. Overall, "TERT-BUTYL 2-(BROMOMETHYL)PHENYLCARBAMATE" is a versatile compound with potential uses in drug development, material science, and other fields of chemistry.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 5344-90-1 2-Aminobenzyl alcohol 
• 164226-32-8 2-(tert-butyloxycarbonyl)aminobenzyl alcohol 

Downstream Products

• 1006899-00-8 tert-Butyl {2-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}carbamate 
• 1159987-58-2 tert-butyl (2-(3-(4-methoxyphenyl)prop-2-yn-1-yl)phenyl)carbamate 
• 608525-30-0 (S)-2-isopropyl-1,2,3,4-tetrahydroquinoline 
• 608525-30-0 (R)-2-isopropyl-1,2,3,4-tetrahydroquinoline 
• 1613-32-7 2-n-Propylquinoline 
• 612-96-4 2-Phenylquinoline 
• 88062-14-0 1,4-dihydro 2-phenyl quinoline 
• 108716-00-3 2-(3-phenylprop-2-enyl)aniline 
• 263154-36-5 C₂₉H₂₉N₇O₇S₃ 
• 1159987-56-0 C₂₀H₂₁NO₂ 
• 1159987-64-0 C₁₉H₂₇NO₂ 

Relevant articles and documents

Photoredox-Catalyzed Trifluoromethylative Intramolecular Cyclization: Synthesis of CF3-Containing Heterocyclic Compounds

A general photoredox-catalyzed intramolecular cyclization was developed for the synthesis of trifluoromethylated heterocyclic compounds. The reaction proceeded smoothly under mild photocatalytic conditions with high functional group tolerance, allowing the preparation of oxygen-, sulfur-, or nitrogen-containing heterocycles of different sizes. The broad substrate scope demonstrated the complexity-building potential of the strategy.

The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processi to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line pu fication.

Construction of Azacycles Based on Endo-Mode Cyclization of Allenes

A new procedure for constructing monocyclic five- and six-membered azacycles by the endo-mode ring-closing reaction of allenylazido derivatives under neutral conditions has been developed. The azabicyclo[m.n.0] compounds were prepared by applying this newly developed procedure. The seven-membered azacycle was prepared when the allene possessing an unsubstituted carboxyl amido functionality was submitted to the basic conditions. In addition, indole and quinoline skeletons were synthesized using this procedure.