16633-50-4

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dimethyl-4-fluorobenzoic acid is used as an intermediate in chemical reactions for the synthesis of various pharmaceutical compounds. Its strong acidic properties make it a valuable component in the development of new drugs and medications.
Used in Manufacturing Industry:
2,6-Dimethyl-4-fluorobenzoic acid is used as a raw material in the production of dyes and other chemicals. Its unique chemical structure allows for the creation of a wide range of products with different properties and applications.
Used in Research and Development:
2,6-Dimethyl-4-fluorobenzoic acid is used as a research compound in various scientific fields, including fluorescence-based biological research. Its potential applications in specialized scientific areas make it an important tool for researchers and scientists.
Used in Chemical Reactions:
2,6-Dimethyl-4-fluorobenzoic acid is used as an intermediate in various chemical reactions within industries such as pharmaceuticals, manufacturing, and research. Its strong acidic behavior and unique chemical structure contribute to the synthesis of a diverse range of products.

InChI:InChI=1/C9H9FO2/c1-5-3-7(10)4-6(2)8(5)9(11)12/h3-4H,1-2H3,(H,11,12)

Upstream product

• 16643-19-9 4-Fluoro-2,6-dimethylbenzamide 
• 110-05-4 di-tert-butyl peroxide 
• 321-21-1 4-fluoro-2-methylbenzoic acid 
• 456-22-4 4-Fluorobenzoic acid 
• 124-38-9 carbon dioxide 
• 14659-58-6 2‐bromo‐5‐fluoro‐1,3‐dimethylbenzene 
• 14659-60-0 methyl 4‐fluoro‐2,6‐dimethylbenzoate 
• 19023-45-1 3,5-dimethyl-4-nitro-benzoic acid amide 
• 14659-61-1 2,6-dimethyl-4-fluorobenzonitrile 
• 315-12-8 2,6-dimethyl-4-fluoro-1-nitro-benzene 
• 3095-38-3 3,5-dimethyl-4-nitrobenzoic acid 
• 392-70-1 2,6-dimethyl-4-fluoroaniline 
• 34761-82-5 3,5-dimethyl-4-nitroaniline 

Downstream Products

• 14659-60-0 methyl 4‐fluoro‐2,6‐dimethylbenzoate 
• 1609401-44-6 4-fluoro-2,6-dimethyl-N-(quinolin-8-yl)benzamide 
• 896120-69-7 4-fluoro-2,6-dimethylbenzoyl chloride 

Relevant academic research and scientific papers

Milled Dry Ice as a C1 Source for the Carboxylation of Aryl Halides

The use of carbon dioxide as a C1 chemical feedstock remains an active field of research. Here we showcase the use of milled dry ice as a method to promote the availability of CO 2in a reaction solution, permitting practical synthesis of arylcarboxylic acids. Notably, the use of milled dry ice produces marked increases in yields relative to those obtained with gaseous CO 2, as previously reported in the literature.

Palladium-Catalyzed ortho-C-H Methylation of Benzoic Acids

A palladium-catalyzed methylation of C-H bonds of benzoic acids with di-tert-butyl peroxide as the methylating reagent under an external oxidant and ligand-free conditions has been achieved. The reaction is found to be directed by a weakly coordinating carboxyl group, offering a facile route for the synthesis of highly functionalized ortho-methyl benzoic acids.

Preparation method for o-tolylacetic acid aryl formic acid derivative

The invention discloses a preparation method for an o-tolylacetic acid aryl formic acid derivative. According to the method, new C-C bonds can be formed, the organic o-tolylacetic acid aryl formic acid derivative is obtained, the good functional group tolerance is achieved, and the o-tolylacetic acid aryl formic acid derivative which cannot be easily obtained by adopting other methods can be synthesized; according to the method, adopted raw materials are easy to obtain, the yield is high, the reaction conditions are mild, the substrate range is wide, and after-treatment is simple and green.

Synthesis and Characterization of Acridinium Dyes for Photoredox Catalysis

Photoredox catalysis is a rapidly evolving platform for synthetic methods development. The prominent use of acridinium salts as a sustainable option for photoredox catalysts has driven the development of more robust and synthetically useful versions based on this scaffold. However, more complicated syntheses, increased cost, and limited commercial availability have hindered the adoption of these catalysts by the greater synthetic community. By utilizing the direct conversion of a xanthylium salt into the corresponding acridinium as the key transformation, we present an efficient and scalable preparation of the most synthetically useful acridinium reported to date. This divergent strategy also enabled the preparation of a suite of novel acridinium dyes, allowing for a systematic investigation of substitution effects on their photophysical properties.

INHIBITORS OF STEAROYL-COA DESATURASE

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.

PIPERAZINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS

The use is described of CCR5 antagonists of formula (I) or a pharmaceutically acceptable salt thereof, wherein: R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R 1 is hydrogen or alkyl; R 2 is substituted phenyl, substituted heteroary

Piperazine derivatives useful as CCR5 antagonists

The use of CCR5 antagonists of the formula or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R1is hydrogen or alkyl; R2is substituted phenyl, substituted heter