166334-81-2

Basic information

• Product Name: {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester
• Synonyms: {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester
• CAS NO: 166334-81-2
• Molecular Weight: 461.558
• Mol File: 166334-81-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester(166334-81-2)
• EPA Substance Registry System: {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester(166334-81-2)

Safety Data

• Hazardous Substances Data: 166334-81-2(Hazardous Substances Data)

Upstream product

• 100058-82-0 5,6,7,8,9,10-Hexahydro-4-hydroxy-2H-cyclooctapyran-2-on 
• 166337-56-0 [3-(1-Hydroxy-propyl)-phenyl]-carbamic acid benzyl ester 
• 67531-69-5 1-(3-aminophenyl)-1-propanol 
• 17408-16-1 3'-nitropropiophenone 

Downstream Products

• 166334-82-3 2H-Cycloocta[b]pyran-2-one, 3-[1-(3-aminophenyl)propyl]-5,6,7,8,9,10-hexahydro-4-hydroxy- 

Relevant articles and documents

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: Exploring the impact of ring size on structure-activity relationships

Previously, 3-substituted cycloalkylpyranones, such as 2d, have proven to be effective inhibitors of HIV protease. In an initial series of 3-(1- phenylpropyl) derivatives with various cycloalkyl ring sizes, the cyclooctyl analog was the most potent. We be