166334-82-3

Basic information

• Product Name: 2H-Cycloocta[b]pyran-2-one, 3-[1-(3-aminophenyl)propyl]-5,6,7,8,9,10-hexahydro-4-hydroxy-
• CAS NO: 166334-82-3
• Molecular Formula: C20H25NO3
• Molecular Weight: 327.423
• Mol File: 166334-82-3.mol

Chemical Properties

• CAS DataBase Reference: 2H-Cycloocta[b]pyran-2-one, 3-[1-(3-aminophenyl)propyl]-5,6,7,8,9,10-hexahydro-4-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Cycloocta[b]pyran-2-one, 3-[1-(3-aminophenyl)propyl]-5,6,7,8,9,10-hexahydro-4-hydroxy-(166334-82-3)
• EPA Substance Registry System: 2H-Cycloocta[b]pyran-2-one, 3-[1-(3-aminophenyl)propyl]-5,6,7,8,9,10-hexahydro-4-hydroxy-(166334-82-3)

Safety Data

• Hazardous Substances Data: 166334-82-3(Hazardous Substances Data)

Upstream product

• 166337-56-0 [3-(1-Hydroxy-propyl)-phenyl]-carbamic acid benzyl ester 
• 67531-69-5 1-(3-aminophenyl)-1-propanol 
• 17408-16-1 3'-nitropropiophenone 
• 166334-81-2 {3-[1-(4-Hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-carbamic acid benzyl ester 

Relevant articles and documents

4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl[b]pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. STR1 Wherein R 10 and R 20 taken together are: STR2

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: Exploring the impact of ring size on structure-activity relationships

Previously, 3-substituted cycloalkylpyranones, such as 2d, have proven to be effective inhibitors of HIV protease. In an initial series of 3-(1- phenylpropyl) derivatives with various cycloalkyl ring sizes, the cyclooctyl analog was the most potent. We be