16635-65-7Relevant academic research and scientific papers
Reaction of 2-hydroxybenzaldehydes with alkynes, alkenes, or allenes via cleavage of the aldehyde C-H bond using a rhodium catalyst system
Kokubo, Ken,Matsumasa, Kenji,Nishinaka, Yuko,Miura, Masahiro,Nomura, Masakatsu
, p. 303 - 311 (1999)
2-Hydroxybenzaldehydes smoothly and efficiently react with various internal and terminal alkynes accompanied by cleavage of the aldehyde C-H bond by using a rhodium-based catalyst system of [RhCl(cod)]2/dppf/Na2CO3 [cod = 1,5-cyclooctadiene; dppf = 1,1'-bis(diphenylphosphino)ferrocene] to give the corresponding 2-alkenoylphenols in good to excellent yields. The regioselectivity of the reaction depends on the substituents of acetylene; an oxygen function on the propargylic position shows a considerable directing effect. The aldehydes can also react with some alkenes or allenes, such as triethylvinylsilane and 2-norbornene or 3-methyl-1,2-butadiene and 1,2- nonadienes, in place of alkynes.
From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si → C Alkyl Rearrangement, and Claisen-Schmidt Condensation
Kumar, Singam Naveen,Bavikar, Suhas Ravindra,Pavan Kumar, Chebolu Naga Sesha Sai,Yu, Isaac Furay,Chein, Rong-Jie
supporting information, p. 5362 - 5366 (2018/09/12)
A highly efficient one-pot procedure was developed for the synthesis of various 2′-hydroxychalcones from phenyl diethylcarbamate, featuring consecutive Snieckus-Fries rearrangement, anionic Si a?' C alkyl rearrangement, and Claisen-Schmidt condensation in a single operation. The applicability of this protocol was demonstrated by the highly efficient synthesis of the anti-inflammatory natural product lonchocarpin. The mechanism insight is also provided.
Synthesis of 3-methylflavones and their antioxidant and antibacterial activities
Jayashree, B. S.,Alam, Afroze,Vijay Kumar, D.,Nayak, Yogendra
, p. 1991 - 1996,6 (2020/07/30)
An attempt was made to synthesise newer 3-methylflavones with various substitution on the ring A and B of 2-phenylchromen-4-one. They were evaluated for antioxidant activity and antibacterial activity against the Gram-positive and Gram-negative bacteria.
Antioxidant and antibacterial activity of new 3-methylflavones
Jayashree,Alam, Afroze,Kumar, D. Vijay,Nayak, Yogendra
scheme or table, p. 237 - 240 (2011/12/15)
Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F-4,9,11,12 and 20
Iridium-catalyzed reaction of 1-naphthols, N-(1-naphthyl)benzenesulfonamides, and salicylaldehyde with internal alkynes
Nishinaka, Yuko,Satoh, Tetsuya,Miura, Masahiro,Morisaka, Hideaki,Nomura, Masakatsu,Matsui, Hisaji,Yamaguchi, Chiharu
, p. 1727 - 1735 (2007/10/03)
1-Naphthols efficiently couple with internal alkynes via cleavage of the C-H bond at the peri-position in the presence of a catalyst system of [IrCl(cod)]2/PBut′3 to selectively afford the corresponding 8-vinyl-1-naphthol derivatives. N-(1-Naphthyl)benzenesulfonamides can similarly react with the alkynes. The reaction of salicylaldehyde with the alkynes using the catalyst system gives 2-hydroxyphenyl vinyl ketones via cleavage of the aldehyde C-H bond.
