166383-74-0

Usage

Derivative of acetic acid

The compound is derived from acetic acid, which means it is structurally related to acetic acid and may share some of its properties.

Benzyl group attachment

The compound contains a benzyl group (a phenyl ring attached to a methyl group) attached to a carbonylaminophenoxy group, which influences its chemical properties and potential applications.

Carbonylaminophenoxy group

This group is a key structural component of the compound, consisting of a carbonyl group (C=O) and an amino group (NH2) attached to a phenoxy group (C6H4-O-).

Pharmaceutical industry applications

2-(4-benzyloxycarbonylaminophenoxy)acetic acid has potential applications in the pharmaceutical industry, particularly in the development of drugs for various medical conditions.

Upstream product

• 166383-75-1 ethyl 4-(N-benzyloxycarbonyl-N-methylamino)phenoxyacetate 
• 166383-73-9 ethyl 4-(benzyloxycarbonylamino)phenoxyacetate 

Downstream Products

• 166382-76-9 1-[(2S,3S)-3-{N₂-[4-(benzyloxycarbonylamino)phenoxyacetyl]-L-asparaginyl}amino-2-hydroxy-4-phenylbutyryl]-N-t-butyl-L-prolinamide 
• 1596360-52-9 methyl 6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxylate 
• 58232-55-6 4-(carbamoylmethoxy)aniline 
• 1596359-98-6 2-[4-(2,4-dioxoimidazolidin-1-yl)phenoxy]acetamide 
• 1596360-89-2 ethyl 2-[[4-(2-amino-2-oxo-ethoxy)phenyl]amino]acetate 
• 694454-63-2 tert-butyl N-[4-(2-amino-2-oxo-ethoxy)phenyl]carbamate 
• 1596360-32-5 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-31-4 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-75-6 9H-fluoren-9-ylmethyl N-[(5S)-5-cyano-5-[[6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]pentyl]carbamate 
• 1596360-74-5 9H-fluoren-9-ylmethyl N-[(5S)-5-[[6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]-5-cyano-pentyl]carbamate 

Relevant academic research and scientific papers

Inhibitors of HIV protease

Compounds of formula (I): STR1 wherein: R1 is hydrogen, alkyl, aralkyl, --CORa, --CORb, --CSRa, --CSRb, --SO2 Rb, --CONHRb, --CSNHRb, --CONRb Rb or --CSNRb Rb ; R2 is hydrogen or alkyl; R3 is hydrogen, alkylidene, substituted alkyl, or Rb ; R4 is optionally substituted alkyl, cycloalkyl, or aryl; R5 is Rb O--, Rb Rb N--, Rb HN--, aralkyloxycarbonyloxy or aralkyloxycarbonylamino, or R5 is --(CH2)p --D--(CH2)r --, where D is a single bond, carbonyl, oxygen, sulfur, --NH--, --(CH2 =CH2)-- or --NHCO--; and p and r are each 0 or an integer from 1 to 5; A is --(CH2)m --B--(CH2)n -- where B is a single bond, carbonyl, oxygen, sulfur, --NH--, --(CH2 =CH2)-- or --NHCO--; and m and n are each 0 or an integer from 1 to 5; Ra is alkoxy, aralkyloxy, aryloxy or alkoxycarbonyl; Rb is optionally substituted alkyl, cycloalkyl, heterocyclic, aryl or arylalkenyl; and pharmaceutically acceptable salts and esters thereof and pro-drugs therefor, have the ability to inhibit the activity of HIV protease and may thus be used for the treatment and prophylaxis of AIDS.