58232-55-6

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-AMINO-PHENOXY)-ACETAMIDE is used as a chemical intermediate for the synthesis of various drugs and pharmaceuticals, playing a crucial role in the development of new medications.
Used in Dye and Pigment Production:
In the dye and pigment industry, 2-(4-AMINO-PHENOXY)-ACETAMIDE is utilized in the production of dyes and organic pigments, contributing to the coloration of various products.
Used in Research for Biological Activities:
2-(4-AMINO-PHENOXY)-ACETAMIDE is studied for its potential antimicrobial and anti-inflammatory properties, indicating its possible use in the development of treatments for infections and inflammatory conditions.

Upstream product

• 59954-04-0 methyl 4-aminophenoxyacetate 
• 63218-14-4 4-nitrophenoxyacetamide 
• 100-02-7 4-nitro-phenol 
• 166383-74-0 2-(4-benzyloxycarbonylaminophenoxy)acetic acid 
• 694454-63-2 tert-butyl N-[4-(2-amino-2-oxo-ethoxy)phenyl]carbamate 

Downstream Products

• 575473-01-7 N₄-(4-aminocarbonylmethyloxyphenyl)-2-chloro-5-fluoro-4-pyrimidineamine 
• 1596360-74-5 9H-fluoren-9-ylmethyl N-[(5S)-5-[[6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]-5-cyano-pentyl]carbamate 
• 1596360-75-6 9H-fluoren-9-ylmethyl N-[(5S)-5-cyano-5-[[6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]pentyl]carbamate 
• 1596360-31-4 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-32-5 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596359-98-6 2-[4-(2,4-dioxoimidazolidin-1-yl)phenoxy]acetamide 
• 1596360-52-9 methyl 6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxylate 
• 575473-00-6 2-chloro-N₄-(4-(cyanomethyloxy)phenyl)-5-fluoro-4-pyrimidineamine 
• 1596360-89-2 ethyl 2-[[4-(2-amino-2-oxo-ethoxy)phenyl]amino]acetate 
• 364626-60-8 C₂₃H₂₀N₄O₃ 
• 1426047-25-7 C₁₆H₁₃ClN₄O₂ 

Relevant academic research and scientific papers

2,4-Pyrimidinediamine Compounds and Their Uses

The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.

Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin

In the development of plasmin inhibitors, a novel chemotype, pyrrolopyrimidine scaffold possessing two motifs, a hydantoin-containing P4 moiety and a warhead-containing P1 moiety, is uncovered. A unique feature of the new line of the plasmin inhibitors is

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

The invention encompasses compounds having formula (I-V) and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.

Condensed 4-aminopyridines with antirheumatic activity

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which one of A or B represents N and the other represents N or C--R3 ; R1 represents hydrogen, halo, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonylalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy, alkoxycarbonyl, alkanoylamino or carbamoylalkenyl; R2 represents hydrogen, alkyl, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, cyano, benzyloxycarbonyl, alkanoyl, benzoyl, alkyl, carboxy, alkylthio or carbamoyl; R5 represents hydrogen or alkyl; R9 represents hydrogen or alkyl; R10 represents phenyl, pyridyl or pyrimidinyl substituted by OR6 and optionally further substituted wherein R6 represents hydrogen, alkyl, alkoxycarbonyl or carbamoyl, alicyclic hydrocarbon, phenyl, cycloalkylalkyl, arylalkyl or pyridyl; or when R10 represents phenyl, OR6 represents a monosaccharide group or a disaccharide group; which are antirheumatic agents. Compositions containing these compounds and processes to prepare them are also disclosed.