1596360-89-2

Upstream product

• 166383-74-0 2-(4-benzyloxycarbonylaminophenoxy)acetic acid 
• 58232-55-6 4-(carbamoylmethoxy)aniline 
• 105-36-2 ethyl bromoacetate 
• 694454-63-2 tert-butyl N-[4-(2-amino-2-oxo-ethoxy)phenyl]carbamate 

Downstream Products

• 1596360-74-5 9H-fluoren-9-ylmethyl N-[(5S)-5-[[6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]-5-cyano-pentyl]carbamate 
• 1596360-75-6 9H-fluoren-9-ylmethyl N-[(5S)-5-cyano-5-[[6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]pentyl]carbamate 
• 1596360-31-4 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-32-5 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-52-9 methyl 6-[[3-[4-(2-amino-2-oxo-ethoxy)phenyl]-2,5-dioxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxylate 
• 1596359-98-6 2-[4-(2,4-dioxoimidazolidin-1-yl)phenoxy]acetamide 

Relevant academic research and scientific papers

Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin

In the development of plasmin inhibitors, a novel chemotype, pyrrolopyrimidine scaffold possessing two motifs, a hydantoin-containing P4 moiety and a warhead-containing P1 moiety, is uncovered. A unique feature of the new line of the plasmin inhibitors is