1664-35-3

Usage

Uses

Used in Pharmaceutical Synthesis:
Ethyl 1-aminocyclopentane-1-carboxylate is utilized as a key building block in the development of pharmaceuticals, contributing to the creation of new drugs with potential therapeutic applications. Its mild and selective reactivity allows for precise chemical modifications, facilitating the synthesis of complex molecular structures.
Used in Agrochemical Synthesis:
In the agrochemical industry, ethyl 1-aminocyclopentane-1-carboxylate serves as a crucial intermediate for the production of various agrochemicals, such as pesticides and herbicides. Its role in these applications is to provide a stable and reactive platform for the synthesis of bioactive compounds that can effectively control pests and weeds in agricultural settings.
Used as a Reagent in Organic Synthesis:
Ethyl 1-aminocyclopentane-1-carboxylate is employed as a reagent in organic synthesis, where its mild and selective reactivity is advantageous for carrying out specific chemical reactions. This property makes it suitable for use in the preparation of a wide range of organic compounds, including those with potential applications in various industries.
Used in the Synthesis of Natural Products:
Given its presence in certain natural products, ethyl 1-aminocyclopentane-1-carboxylate is also used in the synthesis of these bioactive compounds. Its role in this context is to provide a starting material or intermediate that can be further modified to obtain the desired natural product with potential applications in medicine, cosmetics, or other fields.

InChI:InChI=1/C8H15NO2/c1-2-11-7(10)8(9)5-3-4-6-8/h2-6,9H2,1H3

Upstream product

• 64-17-5 ethanol 
• 52-52-8 1-amino-1-cyclopentanecarboxylic acid 
• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 
• 85911-47-3 ethyl N-benzylidene-1-aminocyclopentanecarboxylate 
• 76910-12-8 1-Chlorformyl-1-cyclopentancarbonsaeure-ethylester 
• 699-51-4 1,3-diazaspiro[4.4]nonane-2,4-dione 
• 54378-87-9 1,1-cyclopentanedicarboxylic acid monoethyl ester 
• 4167-77-5 cyclopentane-1,1-dicarboxylic acid diethyl ester 

Downstream Products

• 10316-79-7 (1-aminocyclopentyl)methanol 
• 13908-10-6 1-[3-(2-Chloro-ethyl)-ureido]-cyclopentanecarboxylic acid ethyl ester 
• 95285-30-6 1--cyclpentancarbonsaeure-(1)-ethylester 
• 115572-34-4 1-[(S)-2-((S)-2-Benzyloxycarbonylamino-propionylamino)-propionylamino]-cyclopentanecarboxylic acid ethyl ester 
• 115572-37-7 1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-cyclopentanecarboxylic acid ethyl ester 
• 115572-33-3 ethyl benzyloxycarbonylleucyl-alanyl-1-amino-1-cyclopentanecarboxylate 
• 115572-60-6 1-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-cyclopentanecarboxylic acid ethyl ester 
• 138402-05-8 2-butyl-1,3-diaza-spiro[4.4]non-1-en-4one 
• 115572-55-9 1-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-cyclopentanecarboxylic acid ethyl ester 
• 138402-10-5 trityl irbesartan 
• 13909-05-2 1-({[(2-chloroethyl)nitrosoamino]carbonyl}amino)-cyclopentanecarboxylic acid, ethyl ester 
• 76910-15-1 1,1'-<(5-Nitro-4,6-pyrimidindiyl)diamino>-1,1'-dicyclopentanmethanol 
• 151257-05-5 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-2-en-1-yl)methyl>biphenyl-2-carboxylate 

Relevant academic research and scientific papers

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.

2-(Ethoxycarbonylmethyl)-1H-naphtho[1,8-de]-1,2,3-triazine anion: A new glycine enolate equivalent

The titled triazine can be alkylated with LDA and a variety of alkyl halides: Subsequent reduction with aluminium amalgam cleaves the naphthotriazine moiety to afford substituted α amino acids in excellent overall yields; the sequence defines a novel methodology that can be applied under non-acidic and largely non-aqueous conditions. (C) 2000 Elsevier Science Ltd.

Therapeutic agents

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.

A simple method for the synthesis of cyclic α-amino acids

The benzylidene derivative of glycine ethyl ester was alkylated with various electrophiles to synthesize cyclic α-amino acids bearing aromatic and aliphatic side chains.

Peptide derivatives and processes for their preparation

Peptide ester and amide derivatives of the general formula I: STR1 in which X is H or an acyl, A and B are structurally defined amino acid residues, n is an integer of from 1 to 3, R1 is H or a lower alkyl and either R2 or C is a def

A FACILE PROCEDURE FOR THE PREPARATION OF ALICYCLIC α-AMINO ACIDS

A convenient method for the preparation of alicyclic α-amino acids is described which utilizes ethyl isocyanoacetate and the appropriate dibromo-substituted aliphatic alkylating agent.

Cyclit-Reaktionen, II. Darstellung von Bausteinen zur Synthese carbocyclischer Furanose-Analoga

The four isomeric hydroxycyclopentenmethanols 6a to 9a can easily be made by allylhydroxylation of the epoxides 2 and 4 with phenyl selenide.In a second way the pair 8a and 9a has been synthesized from 11 via 15.As the preparation of 20 demonstrates, the functionalisation of 6a to 9a to carbocyclic furanoses is possible.The dicarboxylic diethyl esters 23 and 33 can be converted into models for carbocyclic ketofuranoses.

Synthesis of 1,1-Diphenylaminoalcohols

The synthesis of 2-amino-2-methyl-1,1-diphenyl-1-propanol (2a) and some of its aryl- and N-substituted derivatives from amino acid esters and Grignard compounds is described.The limits of this synthesis are reported, and so are other methods for the synthesis of amino alcohols.