1664-35-3

Basic information

• Product Name: ethyl 1-aminocyclopentane-1-carboxylate
• Synonyms: ethyl 1-aminocyclopentane-1-carboxylate hydrochloride;ethyl 1-aminocyclopentane-1-carboxylate;ethyl 1-aminocyclopentanecarboxylate(SALTDATA: HCl);Cyclopentanecarboxylic acid, 1-aMino-, ethyl ester;1-amino-1-cyclopentanecarboxylic acid ethyl ester hydrochloride;1-aminocyclopentane-1-carboxylic acid ethyl ester hydrochloride
• CAS NO: 1664-35-3
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.2102
• Mol File: 1664-35-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 207.6 °C at 760 mmHg
• Flash Point: 77.4 °C
• Appearance: /
• Density: 1.056 g/cm³
• Vapor Pressure: 0.223mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.27±0.20(Predicted)
• CAS DataBase Reference: ethyl 1-aminocyclopentane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-aminocyclopentane-1-carboxylate(1664-35-3)
• EPA Substance Registry System: ethyl 1-aminocyclopentane-1-carboxylate(1664-35-3)

Safety Data

• Hazardous Substances Data: 1664-35-3(Hazardous Substances Data)

Usage

Description

Ethyl 1-aminocyclopentane-1-carboxylate is an organic chemical compound characterized by its molecular formula C8H15NO2. It is an ester derivative of aminocyclopentane carboxylic acid, known for its colorless liquid form with a faint odor and solubility in organic solvents. ethyl 1-aminocyclopentane-1-carboxylate is recognized for its mild and selective reactivity, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. Ethyl 1-aminocyclopentane-1-carboxylate can also be found in certain natural products and is accessible through various chemical synthesis methods.

Uses

Used in Pharmaceutical Synthesis:
Ethyl 1-aminocyclopentane-1-carboxylate is utilized as a key building block in the development of pharmaceuticals, contributing to the creation of new drugs with potential therapeutic applications. Its mild and selective reactivity allows for precise chemical modifications, facilitating the synthesis of complex molecular structures.
Used in Agrochemical Synthesis:
In the agrochemical industry, ethyl 1-aminocyclopentane-1-carboxylate serves as a crucial intermediate for the production of various agrochemicals, such as pesticides and herbicides. Its role in these applications is to provide a stable and reactive platform for the synthesis of bioactive compounds that can effectively control pests and weeds in agricultural settings.
Used as a Reagent in Organic Synthesis:
Ethyl 1-aminocyclopentane-1-carboxylate is employed as a reagent in organic synthesis, where its mild and selective reactivity is advantageous for carrying out specific chemical reactions. This property makes it suitable for use in the preparation of a wide range of organic compounds, including those with potential applications in various industries.
Used in the Synthesis of Natural Products:
Given its presence in certain natural products, ethyl 1-aminocyclopentane-1-carboxylate is also used in the synthesis of these bioactive compounds. Its role in this context is to provide a starting material or intermediate that can be further modified to obtain the desired natural product with potential applications in medicine, cosmetics, or other fields.

InChI:InChI=1/C8H15NO2/c1-2-11-7(10)8(9)5-3-4-6-8/h2-6,9H2,1H3

Upstream product

• 64-17-5 ethanol 
• 52-52-8 1-amino-1-cyclopentanecarboxylic acid 
• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 
• 85911-47-3 ethyl N-benzylidene-1-aminocyclopentanecarboxylate 
• 4167-77-5 cyclopentane-1,1-dicarboxylic acid diethyl ester 
• 54378-87-9 1,1-cyclopentanedicarboxylic acid monoethyl ester 
• 76910-12-8 1-Chlorformyl-1-cyclopentancarbonsaeure-ethylester 
• 699-51-4 1,3-diazaspiro[4.4]nonane-2,4-dione 

Downstream Products

• 115572-37-7 1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-cyclopentanecarboxylic acid ethyl ester 
• 138402-05-8 2-butyl-1,3-diaza-spiro[4.4]non-1-en-4one 
• 138402-10-5 trityl irbesartan 
• 13909-05-2 1-({[(2-chloroethyl)nitrosoamino]carbonyl}amino)-cyclopentanecarboxylic acid, ethyl ester 
• 76910-15-1 1,1'-<(5-Nitro-4,6-pyrimidindiyl)diamino>-1,1'-dicyclopentanmethanol 
• 115572-55-9 1-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-cyclopentanecarboxylic acid ethyl ester 
• 151257-05-5 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-2-en-1-yl)methyl>biphenyl-2-carboxylate 
• 138402-11-6 2-butyl-3-{4-[2-(1H-tetrazol-5-yl)phenyl]benzyl}-1,3-diazaspiro[4.4]non-1-en-4-one 
• 151257-04-4 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>nonan-1-yl)methyl>biphenyl-2-carboxylate 
• 151257-08-8 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>nonan-3-yl)methyl>biphenyl-2-carboxylate 
• 138401-34-0 tert-butyl-4'-<(2-n-butyl-4-thioxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate 
• 138401-20-4 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate 

Relevant articles and documents

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.

Therapeutic agents

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.

Peptide derivatives and processes for their preparation

Peptide ester and amide derivatives of the general formula I: STR1 in which X is H or an acyl, A and B are structurally defined amino acid residues, n is an integer of from 1 to 3, R1 is H or a lower alkyl and either R2 or C is a def