16643-55-3

Basic information

• Product Name: 2,5-dimethyl-3,4-diphenylcyclopent-2-en-1-one
• CAS NO: 16643-55-3
• Molecular Formula: C₁₉H₁₈O
• Molecular Weight: 262.3456
• Mol File: 16643-55-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 336.6°C at 760 mmHg
• Flash Point: 155.8°C
• Density: 1.08g/cm³
• Vapor Pressure: 0.000111mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 2,5-dimethyl-3,4-diphenylcyclopent-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dimethyl-3,4-diphenylcyclopent-2-en-1-one(16643-55-3)
• EPA Substance Registry System: 2,5-dimethyl-3,4-diphenylcyclopent-2-en-1-one(16643-55-3)

Safety Data

• Hazardous Substances Data: 16643-55-3(Hazardous Substances Data)

Usage

General Description

2,5-dimethyl-3,4-diphenylcyclopent-2-en-1-one, also known as 2,5-Dimethyl-3,4-diphenyl-2-cyclopenten-1-one, is an organic compound with the molecular formula C20H20O. It is a yellow to brown crystalline solid that is used in the production of pharmaceuticals, as a flavoring agent, and in the synthesis of other organic compounds. It is a cyclic ketone with two methyl groups and two phenyl groups attached to the cyclopentene ring. It is important to handle this chemical with caution as it may have hazardous properties, including skin and eye irritation, and should be stored and used in a well-ventilated area.

Upstream product

• 42124-16-3 1,5-diphenyl-2,4-dimethyl-1,4-pentadien-3-one 
• 100-52-7 benzaldehyde 
• 96-22-0 pentan-3-one 
• 42124-16-3 2,4?dimethyl?1,5?diphenylpenta?1,4?dien?3?one 
• 68226-09-5 r-2,cis-6-diphenyl-trans-3,5-dimethyl-4-oxanone 
• 134-81-6 benzil 
• 5423-06-3 4-hydroxy-2,5-dimethyl-3,4-diphenylcyclopent-2-enone 
• 5141-38-8 2,5-Dimethyl-3,4-diphenyl-cyclopent-2-en-1,4-diol 
• 56406-94-1 1,7-Dimethyl-8,9-diphenyl-3,5-dioxa-tricyclo[5.2.1.0^2,6]dec-8-ene-4,10-dione 
• 75391-07-0 2-methyl-1-phenylpent-1-en-3-one 
• 446873-32-1 7-hydroxy-1.4-dimethyl-2.3.5-triphenyl-norbornene-⁽²⁾ 
• 13360-84-4 2,5-dimethyl-3,4-diphenylcyclopenta-2,4-dione dimer 

Downstream Products

• 67209-33-0 2,5-dimethyl-1,3,4-triphenyl-cyclopentadiene 
• 4916-74-9 (3,5-dimethylcyclopenta-2,5-diene-1,2-diyl)dibenzene 
• 65007-15-0 1,4-dimethyl-2,3-diphenyl-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione 
• 5141-37-7 2,5-Dimethyl-3,4-diphenyl-cyclopent-2-en-1-ol 

Relevant articles and documents

Interrupting Nazarov Reaction with Different Trapping Modality: Utilizing Potassium Alkynyltrifluoroborate as a σ-Nucleophile

The putative oxyallyl cation intermediate generated following Nazarov cyclization of dienone has been successfully intercepted with potassium alkynyltrifluoroborates which act as σ-nucleophiles in the presence of BF3·Et2O. This new t

Reagent-free Nazarov cyclisations

A new protocol for Nazarov cyclisation is described that involves simple heating of dienones in the absence of any external Lewis acid. The Royal Society of Chemistry 2005.

Pd(II)-Catalyzed Enantioselective Desymmetrization of Polycyclic Cyclohexenediones: Conjugate Addition versus Oxidative Heck

Pd(II)-catalyzed desymmetrization of polycyclic cyclohexenediones has been achieved with high enantio- and diastereoselectivities. Up to five contiguous stereocenters are desymmetrized, while simultaneously, an additional stereocenter is created by the enantioselective conjugate addition. Surprisingly, the conjugate addition products dominate even under typical oxidative Heck conditions, and these observations may provide some insight into the competition between the two related reactions.