67209-33-0Relevant academic research and scientific papers
Mild boronic acid catalyzed Nazarov cyclization of divinyl alcohols in tandem with Diels-Alder cycloaddition
Zheng, Hongchao,Lejkowski, Michal,Hall, Dennis G.
supporting information, p. 91 - 94 (2013/02/21)
Boronic acid catalysis (BAC) was applied to a sequential Nazarov cyclization of divinyl alcohols/Diels-Alder cycloadditions leading to the preparation of highly functionalized bicyclic compounds in a highly diastereoselective fashion. In these one-pot transformations, highly functionalized dienes were generated in situ through boronic acid catalyzed Nazarov cyclizations of divinyl alcohols and were subsequently trapped with different dienophiles such as maleic anhydride and phenylmaleimide. The tandem reactions proceed directly from divinyl alcohols under very mild reaction conditions using air-stable catalysts, and as such this methodology represents a greener alternative to existing methods employing strong Lewis and Bronsted acids.
Synthesis of multisubstituted cyclopentadienes from cyclopentenones prepared via catalytic double aldol condensation and nazarov reaction sequence
Nishina, Yuta,Tatsuzaki, Tomohiro,Tsubakihara, Ayano,Kuninobu, Yoichiro,Takai, Kazuhiko
, p. 2585 - 2589 (2011/11/29)
The rhenium-catalyzed synthesis of cyclopentenone derivatives via double aldol condensation and successive Nazarov reaction is described. The cyclopentenones were converted to the corresponding cyclopentadienes using organolithium reagents. Cyclopentadien
