166451-14-5Relevant academic research and scientific papers
First total synthesis of (Z)-11-(2-oxopropylidene)-2,3,11,11a-tetrahydro- 1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5(10H)-one
More, Satish S.,Shanmughapriya,Lingam,Patel
experimental part, p. 2058 - 2066 (2009/10/24)
The first total synthesis of naturally occurring (Z)-11-(2-oxopropylidene)- 2,3,11,11a-tetrahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5(10H)-one,a unique cycloanthranilylproline derivative, has been achieved from readily available anthranilic acid in f
A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimers
Kamal, Ahmed,Shankaraiah,Markandeya,Reddy, K. Laxma,Reddy, Ch. Sanjeeva
, p. 1465 - 1468 (2008/09/18)
A new synthetic pathway has been developed for the preparation of imine-containing pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and their dimers. Selective reduction of aromatic azides as well as aliphatic amides in a single step leading to an intramolecular
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via an intramolecular aza-Wittig reaction. Synthesis of the antibiotic DC-81
Molina, Pedro,Diaz, Isidora,Tarraga, Alberto
, p. 5617 - 5630 (2007/10/02)
A new and efficient synthesis of the pyrrolo[2,1-c][1,4]benzodiazepine ring system has been carried out using, as a key step, an intramolecular aza-Wittig reaction of the appropriately substituted N-(2-azidobenzoyl)pyrrolidine-2-carboxaldehydes. The paren
