1666-01-9Relevant articles and documents
Carbamoylmethylphosphinoxide derivatives based on the triphenylmethane skeleton. Synthesis and extraction properties
Rudzevich, Valentyn,Schollmeyer, Dieter,Braekers, Damien,Desreux, Jean F.,Diss, Romain,Wipff, Georges,Boehmer, Volker
, p. 6027 - 6033 (2005)
Two different strategies were used to synthesize tri(2-alkoxy-5- nitrophenyl)methanes 6a,b. The X-ray structures of 6a and its precursor 5 show the molecules in a conformation with a syn-orientation of the nitro and alkoxy groups. Hydrogenation and acylat
Preparation method of cycloalkylaminophenol intermediate (by machine translation)
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Paragraph 0061-0065, (2019/08/20)
The invention provides a preparation method, of a cycloalkylaminophenol intermediate. The method comprises the following steps: A) reacting an alkyl-substituted phenol, hexamethylenetetramine and acetic acid or a derivative thereof, obtaining first crude product; B) reacting the first crude product and the cycloalkylamine compound to obtain second crude product; C) reacting the second crude, the hydrogenated reducing agent in an alcohol solvent, and obtaining an aminophenol intermediate. The preparation method of the cycloalkylaminophenol intermediate is simple in process, mild in condition, and mild in condition. The prepared alkylaminophenol intermediate has good purity and yield, and is suitable for industrial production. (by machine translation)
Salicylaldehyde Hydrazones: Buttressing of Outer-Sphere Hydrogen-Bonding and Copper Extraction Properties
Roach, Benjamin D.,Lin, Tai,Bauer, Heiko,Forgan, Ross S.,Parsons, Simon,Rogers, David M.,White, Fraser J.,Tasker, Peter A.
, p. 556 - 565 (2017/05/09)
Salicylaldehyde hydrazones are weaker copper extractants than their oxime derivatives, which are used in hydrometallurgical processes to recover ~20% of the world's copper. Their strength, based on the extraction equilibrium constant Ke, can be increased by nearly three orders of magnitude by incorporating electron-withdrawing or hydrogen-bond acceptor groups (X) ortho to the phenolic OH group of the salicylaldehyde unit. Density functional theory calculations suggest that the effects of the 3-X substituents arise from a combination of their influence on the acidity of the phenol in the pH-dependent equilibrium, Cu2++2Lorg→[Cu(L-H)2]org+2H+, and on their ability to 'buttress' interligand hydrogen bonding by interacting with the hydrazone N-H donor group. X-ray crystal structure determination and computed structures indicate that in both the solid state and the gas phase, coordinated hydrazone groups are less planar than coordinated oximes and this has an adverse effect on intramolecular hydrogen-bond formation to the neighbouring phenolate oxygen atoms.