166655-28-3Relevant academic research and scientific papers
Synthesis of constrained α-amino acid derivatives via ring-closing olefin metathesis
Kotha, Sambasivarao,Sreenivasachary, Nampally
, p. 257 - 260 (1998)
Five and seven membered constrained α-amino acid derivatives were synthesized using ring-closing metathesis reaction as a key step.
Microwave-assisted synthesis of γ-thiolactams from ethyl isocyanoacetate
Lamberto, Massimiliano
, p. 125 - 128 (2018)
γ-Thiolactams were synthesized in good yields from ethyl isocyanoacetate through a sequential alkylation/isothiocyanation/radical cyclization under microwave irradiation.
Synthesis of constrained α-amino acid derivatives via enyne metathesis reaction
Kotha, Sambasivarao,Sreenivasachary, Nampally,Brahmachary, Enugurthi
, p. 2805 - 2808 (1998)
Synthesis of a diene building block via enyne metathesis reaction and its usage in the preparation of constrained α-amino acid derivatives is described.
Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide
Wang, Jian,Tang, Shi,Zhu, Qiang
supporting information, p. 3074 - 3077 (2016/07/13)
Efficient access to five- to seven-membered cyclic ketoimines, through palladium-catalyzed intramolecular imidoylative Heck reaction of alkene-containing isocyanides, has been developed. Consecutive isocyanide and alkene insertion into aryl or alkyl Pd(II) intermediates takes place in this process. No byproduct derived from monoinsertion or reversed sequence is detected.
Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide
Dietrich, Silvia Anthoine,Banfi, Luca,Basso, Andrea,Damonte, Gianluca,Guanti, Giuseppe,Riva, Renata
, p. 97 - 106 (2007/10/03)
A conformationally restricted cyclic pentapeptide, containing an unsaturated 9-membered lactam as a semi-rigid scaffold, was prepared in a very convergent manner, through tandem Ugi reaction/ring closing metathesis.
Constrained phenylalanine derivatives by enyne metathesis and Diels-Alder reaction
Kotha, Sambasivarao,Sreenivasachary, Nampally,Brahmachary, Enugurthi
, p. 787 - 792 (2007/10/03)
A conceptually new approach for the synthesis of indane-based α-amino acid derivatives is reported. In this regard, the synthesis of five-membered exocyclic and five-membered inner-outer ring diene building blocks (7 and 15) containing α-amino acid moieties is described. Diene 15 is prepared by an enyne metathesis reaction as a key step. In this paper, a full account of our work regarding the Diels-Alder reaction of these dienes with various dienophiles, and the subsequent oxidation of the cycloadducts to give various indane-based α-amino acid derivatives is reported.
Thiol-Mediated Free Radical Cyclization of Alkenyl and Alkynyl Isocyanides
Bachi, Mario D.,Balanov, Anna,Bar-Ner, Nira
, p. 7752 - 7758 (2007/10/02)
Thiol-mediated free radical cyclizations of but-3-enyl and but-3-ynyl isocyanides of types 6-8 give new access to 3,5-disubstituted 2-(alkyl- and 2-(arylthio)pyrrolines 11, 12, and 18.When 2-mercaptoethanol is used with the same isocyanides the reaction r
