16668-83-0Relevant articles and documents
Oxygenation of alkane C-H bonds with methyl(trifluoromethyl)dioxirane: Effect of the substituents and the solvent on the reaction rate
Gonzalez-Nunez, Maria E.,Royo, Jorge,Mello, Rossella,Baguena, Minerva,Ferrer, Jaime Martinez,De Arellano, Carmen Ramirez,Asensio, Gregorio,Prakash, G. K. Surya
, p. 7919 - 7924 (2005)
The mechanism of the oxygenation of alkane C-H bonds with methyl(trifluoromethyl)dioxirane (1a) is studied through the effect of the substituent and solvent on the rate of oxygenation of 2-substituted adamantanes (2). The results suggest a remarkable elec
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Olah,G.A.,Prakash,G.K.,Shih,J.G.
, p. 2764 (1985)
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Olah,G.A.,Sigh,J.G.,Krishnamurthy,V.V.
, p. 4492 (1984)
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Applications of the bloch-siegert shift in solid-state proton-dipolar-decoupled 19F MAS NMR
Vierkoetter, Stephanie A.
, p. 84 - 93 (1996)
In solid-state proton-dipolar-decoupled 19F MAS NMR spectroscopy, 19F chemical-shift data need to be corrected for the BlochSiegert shift. Assigning the single sharp 19F resonance of 2-fluoroadamantane to its proton-coupled 19F shift of -174.4 ppm results in chemical-shift referencing that is independent of the amplitude of the proton-decoupling field. The Bloch-Siegert shift is also a useful tool to characterize the amplitude and homogeneity of the proton-decoupling field, H1H, and to monitor probe performance. Considerable inhomogeneity in H1H along the long axis of the rightcylinder sample rotor was detected. In our commercial 7 mm H-F MAS probe, the proton field strength, A HH1H, decreases to 25% of the maximum value across the usable sample volume. Measurement of the Bloch-Siegert shift revealed that the proton-decoupling field strength decreases during the first few scans of an acquisition. Reductions in the proton field strengths can exceed 10%, and they are explained by the heating of the RF coil circuitry which is caused by high-power proton decoupling. The extent of reduction in field amplitude is a function of the decoupling duty cycle. Losses in A HH1H can be avoided by tuning the probe proton RF circuitry at the operating temperature of the probe, using the Bloch-Siegert shift as an optimization parameter.
Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor
González-Esguevillas, María,Miró, Javier,Jeffrey, Jenna L.,MacMillan, David W.C.
supporting information, p. 4222 - 4227 (2019/06/13)
Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C–F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols.
C-HALOGEN BOND FORMATION
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Paragraph 0139-0140; 0142-0144; 0151; 0163-0164, (2013/03/26)
Methods of halogenating a carbon containing compound having an sp3 C-H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C-H fluorination of a carbon containing compound having an sp3 C-H bond are provided. The halogenated products of the methods are provided.
A polycomponent metal-catalyzed aliphatic, allylic, and benzylic fluorination
Bloom, Steven,Pitts, Cody Ross,Miller, David Curtin,Haselton, Nathan,Holl, Maxwell Gargiulo,Urheim, Ellen,Lectka, Thomas
, p. 10580 - 10583,4 (2020/09/02)
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