20098-20-8

Basic information

• Product Name: 5-BROMO-2-ADAMANTANONE
• Synonyms: 5-BROMO-2-ADAMANTANONE,98.0%(GC);1-Bromoadamantan-4-one, 5-Bromotricyclo[3.3.1.13,7]decanone;5-Bromotricyclo[3.3.1.13,7]decanone;5-Bromo-2-adamantanone;5-BROMO-2-ADAMANTANONE5
• CAS NO: 20098-20-8
• Molecular Formula: C₁₀H₁₃BrO
• Molecular Weight: 229.11
• Product Categories: Adamantanes
• Mol File: 20098-20-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 153 °C
• Boiling Point: 295.3 °C at 760 mmHg
• Flash Point: 88.4 °C
• Appearance: /
• Density: 1.579 g/cm³
• Vapor Pressure: 0.00154mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 5-BROMO-2-ADAMANTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-ADAMANTANONE(20098-20-8)
• EPA Substance Registry System: 5-BROMO-2-ADAMANTANONE(20098-20-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 20098-20-8(Hazardous Substances Data)

Usage

General Description

5-BROMO-2-ADAMANTANONE is a chemical compound with the molecular formula C10H13BrO. It is a brominated derivative of 2-adamantanone, which is a cyclic ketone. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has also been studied for its potential applications in medicinal and material science. 5-BROMO-2-ADAMANTANONE is known for its high stability and low reactivity, making it a valuable building block in organic synthesis. Overall, this chemical compound has garnered interest for its versatile applications in various fields of research and industry.

InChI:InChI=1/C10H13BrO/c11-10-3-6-1-7(4-10)9(12)8(2-6)5-10/h6-8H,1-5H2

Upstream product

• 20098-14-0 chemantane 
• 700-58-3 2-Adamantanone 
• 700-57-2 1-adamantanol 

Downstream Products

• 38584-33-7 5-phenyladamantan-2-one 
• 20098-14-0 chemantane 
• 41171-83-9 5-fluoroadamantan-2-one 
• 16668-83-0 2-fluoroadamantane 

Relevant articles and documents

Adamantane sulfone and sulfonamide 11-β-HSD1 Inhibitors

Potent and selective adamantane sulfone and sulfonamide inhibitors of 11-β-HSD-1 have been discovered. Selected compounds from these series have robust pharmacokinetic profiles and strongly inhibit liver, fat, and brain HSD1 for extended periods after ora

Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand

(Figure presented) The complexatlon properties of two novel C5-substituted adamantanediazirines within the resorcin[4]arene-based cavitand 4 were investigated In DMSO-d6, revealing that binding Is up to 1.4 kcal/mol stronger for halogenated adamantanediazirines when compared with the unsubstituted species. The thermal behavior of 5-bromo-2-aziadamantane (3) was investigated by DSC analysis as the first representative of the adamantanediazirine family In the neat solid state, as well as encapsulated within the aromatic cavity of cavitand 4. In the solid phase, the reactions of photolytically or thermolytically generated 5-bromo-2-adamantanylldene (11) can be controlled by complexation within cavitand 4.

Reversal of diastereoselectivities in intra- and intermolecular reactions of 2-adamantanylidenes primarily caused by electron-donating and electron-withdrawing substituents on C5

(Matrix presented) A reversal of diastereoselectivity was observed for novel 5-(trimethylsilyl)adamantan-2-ylidene (1c) with regard to 5-hydroxyadamantan-2-ylidene (1a). Ostensibly in intermolecular reactions, 5-substituted 2-adamantanylidenes (1) are ste