16673-96-4Relevant academic research and scientific papers
Comparison of small molecule inhibitors of the bacterial cell division protein ftsz and identification of a reliable cross-species inhibitor
Anderson, David E.,Kim, Michelle B.,Moore, Jared T.,O'Brien, Terrence E.,Sorto, Nohemy A.,Grove, Charles I.,Lackner, Laura L.,Ames, James B.,Shaw, Jared T.
, p. 1918 - 1928 (2012)
FtsZ is a guanosine triphosphatase (GTPase) that mediates cytokinesis in bacteria. FtsZ is homologous in structure to eukaryotic tubulin and polymerizes in a similar head-to-tail fashion. The study of tubulin's function in eukaryotic cells has benefited g
