Comparison of small molecule inhibitors of the bacterial cell division protein ftsz and identification of a reliable cross-species inhibitor

Article abstract of DOI:10.1021/cb300340j

FtsZ is a guanosine triphosphatase (GTPase) that mediates cytokinesis in bacteria. FtsZ is homologous in structure to eukaryotic tubulin and polymerizes in a similar head-to-tail fashion. The study of tubulin's function in eukaryotic cells has benefited g