16676-75-8 Usage
General Description
Vitamin E nicotinate is a chemical compound that is composed of nicotinic acid and vitamin E. It is a form of vitamin E that has been esterified with nicotinic acid. Vitamin E nicotinate is known for its antioxidant properties, which help to protect the body from damage caused by free radicals. It also has potential vasodilatory and anti-inflammatory effects, making it useful in the treatment of certain cardiovascular and dermatological conditions. Additionally, it has been studied for its potential role in improving blood flow and circulation, as well as its ability to support skin health. Vitamin E nicotinate is commonly used as an ingredient in skincare products and dietary supplements for its potential health benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 16676-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,7 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16676-75:
(7*1)+(6*6)+(5*6)+(4*7)+(3*6)+(2*7)+(1*5)=138
138 % 10 = 8
So 16676-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C35H53NO3/c1-24(2)13-9-14-25(3)15-10-16-26(4)17-11-20-35(8)21-19-31-29(7)32(27(5)28(6)33(31)39-35)38-34(37)30-18-12-22-36-23-30/h12,18,22-26H,9-11,13-17,19-21H2,1-8H3/t25-,26-,35+/m1/s1
16676-75-8Relevant articles and documents
Synthesis method of tocopherol nicotinate
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Paragraph 0008; 0016; 0018-0033, (2021/10/30)
The invention belongs to the technical field of organic chemical synthesis, and relates to a method for preparing tocopherol nicotinate from 3-pyridylaldehyde and tocopherol. According to the method, 3-pyridylaldehyde and tocopherol are used as raw materials, N-heterocyclic carbene is used as a catalyst, and tocopherol nicotinate is synthesized through oxidative esterification. The method has the advantages of cheap raw materials, mild reaction conditions, simple process, greenness, safety, high efficiency and environmental protection, and is suitable for industrial production.
One-pot preparation of esters from carboxylic acids using the PPh3-CCl3CN system
Jang, Doo Ok,Cho, Dae Hyan,Kim, Joong-Gon
, p. 2885 - 2890 (2007/10/03)
A convenient one-pot process for preparing various esters from carboxylic acids using the Ph3P-CCl3CN has been developed. Racemic α-tocopherol, clofibrate and flavoxate were prepared in high yields using this method.
N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORDIAMIDIC CHLORIDE (CLSPO): A NEW STRATEGY FOR THE ESTER FUNCTION PREPARATION
Ballester-Rodes, M.,Palomo-Coll, A. L.
, p. 515 - 520 (2007/10/02)
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