166765-06-6

Basic information

• Product Name: 2-Furancarboxamide,tetrahydro-N-methyl-5-oxo-,(2R)-(9CI)
• Synonyms: 2-Furancarboxamide,tetrahydro-N-methyl-5-oxo-,(2R)-(9CI);(2R)-N-methyl-5-oxooxolane-2-carboxamide
• CAS NO: 166765-06-6
• Molecular Formula: C6H9NO3
• Molecular Weight: 143.14
• Product Categories: AMIDE
• Mol File: 166765-06-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Furancarboxamide,tetrahydro-N-methyl-5-oxo-,(2R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxamide,tetrahydro-N-methyl-5-oxo-,(2R)-(9CI)(166765-06-6)
• EPA Substance Registry System: 2-Furancarboxamide,tetrahydro-N-methyl-5-oxo-,(2R)-(9CI)(166765-06-6)

Safety Data

• Hazardous Substances Data: 166765-06-6(Hazardous Substances Data)

Upstream product

• 53558-93-3 (R)-tetrahydro-5-oxo-2-furancarboxylic acid 
• 6893-26-1 D-Glutamic acid 
• 53558-94-4 (R)-(-)-γ-chlorocarbonyl-γ-butyrolactone 
• 74-89-5 methylamine 

Relevant articles and documents

Lactones, part 28: EPC-Synthesis, structure and pharmacology of 'lactonized' and 'lactamized' analogues of acetylcholine

The enantiopure γ-aminomethyl-γ-butyrolactones (S)- and (R)-4a-d represent constrained analogues of acetylcholine, which were synthesized from D- or L-glutamic acid following two different routes. In addition, the corresponding lactames (S)- and (R)-10 were prepared by enantioselective synthesis. Only moderate activity was found at acetylcholine sites at the guinea pig atrium.