166803-31-2

Basic information

• Product Name: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dioxo-, ethyl ester, (6E)-
• CAS NO: 166803-31-2
• Molecular Formula: C27H24FNO4
• Molecular Weight: 445.49
• Mol File: 166803-31-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dioxo-, ethyl ester, (6E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dioxo-, ethyl ester, (6E)-(166803-31-2)
• EPA Substance Registry System: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dioxo-, ethyl ester, (6E)-(166803-31-2)

Safety Data

• Hazardous Substances Data: 166803-31-2(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 116967-26-1 3,5-dioxoheptenoic acid t-butyl ester 
• 121660-37-5 2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline 
• 19841-57-7 ethyl 3,5-dioxohexanoate 
• 148901-69-3 (E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxohept-6-enic acid ethyl ester 
• 108-05-4 vinyl acetate 
• 141-97-9 ethyl acetoacetate 
• 64-19-7 acetic acid 
• 141750-56-3 (E)-3-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-N-methoxy-N-methyl-acrylamide 

Downstream Products

• 147526-32-7 pitavastatin 
• 477950-34-8 ethyl (E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enoate 
• 148901-69-3 (E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxohept-6-enic acid ethyl ester 
• 167073-19-0 (E)-(3R,5S)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester 
• 172336-32-2 (E)-(3R,5S)-7-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester 

Relevant articles and documents

METHOD FOR PRODUCING PITAVASTATIN CALCIUM

Production of pitavastatin calcium safely on an industrial scale with a high yield and high selectivity at low cost. A method of producing pitavastatin calcium including step (i) for acetalizing a compound represented by the formula (1) to give a compound represented by the formula (3), step (ii) for reacting a compound represented by the formula (3) with an acid to give a compound represented by the formula (4), and step (iii) for hydrolyzing a compound represented by the formula (4) and reacting same with a calcium compound.

Process for the manufacture of organic compounds

The invention relates to a process for the manufacture of a compound of formula or a salt, especially a pharmaceutically acceptable salt with a base, thereof or a lactone thereof wherein the element represents —CH2—CH2— or —CH═CH— an