16695-41-3

Basic information

• Product Name: trans-7-dodecenylacetate
• Synonyms: trans-7-dodecenylacetate;(E)-7-Dodecen-1-ol acetate;Acetic acid [(E)-7-dodecene]-1-yl ester;7-Dodecen-1-ol, 1-acetate, (7E)-;7-Dodecen-1-ol, acetate, (7E)-;7-Dodecen-1-ol, acetate, (E)-;Ai3-33267;7E-12Ac
• CAS NO: 16695-41-3
• Molecular Formula: C₁₄H₂₆O₂
• Molecular Weight: 225.3471
• Mol File: 16695-41-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 300.1±21.0℃ (760 Torr)
• Flash Point: 96.5±20.4℃
• Appearance: /
• Density: 0.881±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00114mmHg at 25°C
• Refractive Index: 1.448
• CAS DataBase Reference: trans-7-dodecenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: trans-7-dodecenylacetate(16695-41-3)
• EPA Substance Registry System: trans-7-dodecenylacetate(16695-41-3)

Safety Data

• Hazardous Substances Data: 16695-41-3(Hazardous Substances Data)

Usage

General Description

Trans-7-dodecenylacetate is a chemical compound commonly used as a flavoring agent in the food and beverage industry. It is found naturally in various fruits, such as apples and strawberries, and is responsible for their characteristic fruity aroma. trans-7-dodecenylacetate is also used in the production of perfumes and cosmetics for its pleasant, sweet, floral scent. Additionally, trans-7-dodecenylacetate is often employed in the manufacturing of household products, such as air fresheners and cleaning agents, to impart a fresh and inviting fragrance. The compound is generally considered safe for use in these applications, with no significant known health risks associated with normal exposure levels.

InChI:InChI=1/C14H26O2/c1-3-4-5-6-7-8-9-10-11-12-13-16-14(2)15/h6-7H,3-5,8-13H2,1-2H3/b7-6+

Upstream product

• 592-41-6 1-hexene 
• 5048-35-1 oct-7-en-1-yl acetate 
• 693-03-8 n-butyl magnesium bromide 
• 108-24-7 acetic anhydride 
• 98752-54-6 (Z)-2-(8-phenylthio-oct-7-enyloxy)tetrahydro-2H-pyran 
• 112-62-9 Methyl oleate 
• 14959-86-5 (Z)-7-dodecenyl acetate 
• 127-09-3 sodium acetate 
• 71655-20-4 (E)-12-Bromo-dodec-5-ene 

Relevant articles and documents

Libraries via Metathesis of Internal Olefins

The cross-metathesis of internal olefins is applied for the combinatorial synthesis of small organic molecules; this reaction is conveniently carried out in neat olefin (oleic-acid derivatives) and requires only 0.001 equiv. of [Ru(CHPh)Cl2(PCy3)2] as catalyst (Cy = cyclohexyl).

A General Approach to the Synthesis of Mono-olefinic Insect Sex Pheromones of Z- or E-Configuration

A series of insect sex pheromones and structually related olefins have been synthesized with high stereoisomeric purity by two sequential cross-coupling reactions.Starting with (Z)- or (E)-1-bromo-2-phenylthioethene, (1) and (2), and Grignard reagents in the presence of nickel or palladium catalysts, two types of compounds have been prepared: (i) 1,2-dialkylethenes and (ii) alkenyl acetates.In the synthesis of Z-isomers, the first step involves a cross-coupling reaction of compound (1) with the appropriate Grignard reagent in the presence of a catalytic amount of .The second cross-coupling reaction is performed on the intermediate (Z)-phenylthioalkenes using a different Grignard reagent in the presence of (dppe=Ph2PCH2CH2PPh2) as a catalyst.In the synthesis of E-isomers both steps are cross-coupling reactions of Grignard reagents in the presence of as a catalyst, the first step involving compound (2) and the second step involving the intermediate (E)-phenylthioalkenes obtained.The Grignard reagents used in the synthesis of the alkenyl acetates derive from protected ω-halohydrins.