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2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate, also known as Hydroxy-PEG3-acrylate, is a PEG (polyethylene glycol) based compound that features a hydroxyl group and an acrylate group. The hydroxyl group provides the capacity for further chemical modifications, while the acrylate group facilitates Michael addition reactions. The hydrophilic PEG spacer enhances the compound's solubility in aqueous environments, making it versatile for various applications.

16695-45-7

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16695-45-7 Usage

Uses

Used in Pharmaceutical Industry:
2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate is used as a pharmaceutical excipient for improving the solubility and bioavailability of hydrophobic drugs. The hydrophilic PEG spacer aids in the dispersion of these drugs in aqueous solutions, thereby enhancing their therapeutic efficacy.
Used in Bioconjugation:
In the field of bioconjugation, 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate serves as a versatile linker for attaching biologically active molecules, such as peptides, proteins, or nucleic acids, to various surfaces or nanoparticles. The hydroxyl group allows for covalent attachment, while the PEG spacer provides steric stabilization and reduces non-specific interactions.
Used in Polymer Science:
2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate is utilized as a monomer in the synthesis of hydrophilic polymers. The acrylate group can be polymerized to form polymers with tunable properties, such as molecular weight, architecture, and functionality. These polymers find applications in areas like drug delivery, tissue engineering, and surface modification.
Used in Cosmetics Industry:
In the cosmetics industry, 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate is employed as a component in formulations to improve the solubility and stability of active ingredients. The PEG-based structure contributes to the product's non-irritating and non-toxic nature, making it suitable for use in personal care products.
Used in Material Science:
2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate is used in the development of stimuli-responsive materials, such as hydrogels and micelles, which can undergo structural changes in response to environmental stimuli like temperature, pH, or light. The PEG spacer and hydrophilic nature of the compound contribute to the formation of these responsive materials, with potential applications in drug delivery, sensors, and smart coatings.

Check Digit Verification of cas no

The CAS Registry Mumber 16695-45-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,9 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16695-45:
(7*1)+(6*6)+(5*6)+(4*9)+(3*5)+(2*4)+(1*5)=137
137 % 10 = 7
So 16695-45-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H16O5/c1-2-9(11)14-8-7-13-6-5-12-4-3-10/h2,10H,1,3-8H2

16695-45-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-(2-hydroxyethoxy)ethoxy]ethyl prop-2-enoate

1.2 Other means of identification

Product number -
Other names ethylenediglycol acrylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16695-45-7 SDS

16695-45-7Downstream Products

16695-45-7Relevant academic research and scientific papers

CURED PRODUCT, OPTICAL MEMBER, LENS, COMPOUND, AND CURABLE COMPOSITION

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Paragraph 0254-0256, (2020/07/14)

According to the present invention, a cured product obtained by curing a curable composition including a compound represented by General Formula 1, in which a birefringence Δn (587 nm) is 0.00≤Δn (587 nm)≤0.01, is provided, and this cured product is suitable for manufacturing an optical member. [in-line-formulae]Pol1-Sp1-L1-Ar-L2-Sp2-Pol2??(General Formula 1)[/in-line-formulae] In formula, Ar is an aromatic ring group represented by General Formula 2-2 and the like. In formula, Z1 and Z2 each represent a hydrogen atom, a methyl group, and the like; A1 and A2 each represent —S— and the like; X represents C(Rz)2 and the like (where Rz is a substituent, and two Rz's may form a ring); L1 and L2 each represent a single bond, —O—, —OC(═O)—, —OC(═O)O—, —OC(═O)NH—, and the like; Sp1 and Sp2 each represent a single bond or a divalent linking group; Pol1 and Pol2 each represent a hydrogen atom or a polymerizable group; and a compound represented by General Formula 1 has at least one polymerizable group.

LENS ADHESIVE, CEMENTED LENS, AND IMAGING MODULE

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Paragraph 0274; 0276, (2020/11/30)

According to the present invention, a lens adhesive including a compound represented by General Formula 1 is provided. [in-line-formulae]Pol1-Sp1-L1-Ar-L2-Sp2-Pol2??(General Formula 1)[/in-line-formulae] In the formula, Ar is an aromatic ring group represented by General Formula 2-2 and the like. In the formula, Z1 and Z2 each represent a hydrogen atom, a methyl group, and the like; A1 and A2 each represent —S— and the like; X represents C(Rz)2 and the like (where Rz is a substituent, and two Rz's may form a ring); L1 and L2 each represent a single bond, —O—, —OC(═O)—, —OC(═O)O—, —OC(═O)NH—, and the like; Sp1 and Sp2 each represent a single bond or a linking group such as a linear alkylene group; Pol1 and Pol2 each represent a hydrogen atom or a polymerizable group; and a compound represented by General Formula 1 has at least one polymerizable group. Using the lens adhesive, it is possible to provide a cemented lens that is unlikely to deteriorate due to light, and an imaging module having high durability.

Phosphate cross-linking agent and preparation method thereof, phosphate-based cross-linked gel polymer electrolyte and preparation method and application thereof

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Paragraph 0047-0048; 0054, (2020/08/17)

According to the invention, the safety of the battery can be improved based on introduction of phosphate into the gel polymer electrolyte, , the adjustable flexibility is improved by introduction of aPEO chain segment, and the stability and the polymerization capability are improved by introduction of acrylate; thus, further research is carried out on the basis of the prior art, the polyfunctional phosphate cross-linking agent is obtained and is applied to the preparation of the phosphate-based cross-linked gel polymer electrolyte, so the cross linking agent can be copolymerized with other functional monomers to synthesize gel polymer electrolyte; the gel polymer electrolyte has the advantages of simple and convenient preparation method, high ionic conductivity, high thermal stability andgood electrochemical stability, the assembled sodium ion battery has good cycling stability and high-temperature performance, and the phosphate-based gel polymer electrolyte with high safety is provided for quasi-solid sodium/lithium ion batteries.

METHOD FOR THE PRODUCTION OF HYDROXYALKYL CARBONIC ACID ESTERS

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Page/Page column 19, (2008/06/13)

The invention relates to a heterogeneously catalyzed method for producing hydroxyalkyl carbonic acid esters from carbonic acids and alkylene oxides and the use thereof.

Macrocyclic ethers by free radical cyclizations

Philippon, Annie,Tao, Jingchao,Tetard, David,Degueil-Castaing, Marie,Maillard, Bernard

, p. 2651 - 2682 (2007/10/03)

Tin hydride reduction of ω-iodo-polyoxaalkyl acrylates 1 using syringe pump addition of both reactants to a solution of AIBN in benzene at 80°C afforded the corresponding cyclic polyethers in excellent yields.

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