167256-08-8

Usage

Uses

Used in Organic Chemistry:
(1S,2R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-5-propoxy-2,3-dihydro-1H-indene-2-carboxylic acid is used as a building block for the synthesis of more complex organic molecules due to its diverse functional groups and unique structure.
Used in Pharmaceutical Industry:
(1S,2R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-5-propoxy-2,3-dihydro-1H-indene-2-carboxylic acid is used as a potential pharmaceutical agent for the development of new drugs, given its complex structure and the presence of various functional groups that can interact with biological targets.
Used in Materials Science:
(1S,2R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-5-propoxy-2,3-dihydro-1H-indene-2-carboxylic acid is used as a component in the development of new materials with specific properties, such as polymers or composites, owing to its structural diversity and functional groups.

Upstream product

• 190965-53-8 [1S-(1α,2α,3α)]-methyl 1-(1,3-benzodioxol-5-yl)-2,3-dihydro-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-5-propoxy-1H-indene-2-carboxylate 
• 7732-18-5 water 
• 190969-65-4 (S)-3-(1,3-benzodioxol-5-yl)-6-propoxy-1H-inden-1-ol 
• 190969-66-5 (S)-3-(1,3-benzodioxol-5-yl)-2,3-dihydro-6-propoxy-1H-indan-1-one 
• 191106-49-7 (S)-1-Benzo[1,3]dioxol-5-yl-3-(2-benzyloxy-4-methoxy-phenyl)-5-propoxy-1H-indene-2-carboxylic acid methyl ester 
• 167256-05-5 (+)Methyl-(1S,2S,3S)-3-(2-Hydroxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylate 
• 190969-67-6 (S)-Methyl-1-(1,3-benzodioxol-5-yl)-3-[(fluorosulfonyl)oxy]5-propoxy-1H-indene-2-carboxylate 
• 190969-64-3 (E)-3-Benzo[1,3]dioxol-5-yl-1-(2-bromo-5-propoxy-phenyl)-propenone 
• 174527-88-9 3-(1,3-benzodioxol-5-yl)-6-propoxy-1H-inden-1-one 
• 190969-63-2 1-(2-Bromo-5-propoxyphenyl)ethanone 
• 120-57-0 piperonal 

Relevant academic research and scientific papers

3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives

PCT No. PCT/US96/18465 Sec. 371 Date Feb. 4, 1997 Sec. 102(e) Date Feb. 4, 1997 PCT Filed Nov. 8, 1996 PCT Pub. No. WO97/17341 PCT Pub. Date May 15, 1997Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentanopyridine derivatives. The most preferred compounds prepared by this invention are (+)(1S,2R,3S)-3-[2-(2-hydroxyeth-1-yloxy)-4-methoxyphenyl]-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof and (+)(1S,2R,3S)-3-(2-carboxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxypheyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof. Also invented are novel intermediates useful in preparing these compounds.

Stereoselective synthesis of endothelin receptor antagonists

PCT No. PCT/US96/18084 Sec. 371 Date May 8, 1998 Sec. 102(e) Date May 8, 1998 PCT Filed Nov. 8, 1996 PCT Pub. No. WO97/17071 PCT Pub. Date May 15, 1997The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates

Stereoselective synthesis of endothelin receptor antagonists

The present invention is directed to chiral intermediates in a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A). STR1

Endothelin receptor antagonists

Novel indane and indene derivatives are described which are endothelin receptor antagonists.