167279-18-7

Usage

Uses

Used in Pharmaceutical Research:
ETHYL 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLATE is used as a research compound for its potential pharmacological properties. It has been studied for its potential as an anti-inflammatory and anticonvulsant agent, indicating its possible use in the development of medications for treating inflammation and seizure disorders.
Used in Organic Synthesis:
In the field of organic synthesis, ETHYL 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLATE serves as a key intermediate or building block in the synthesis of more complex organic molecules. Its unique structure, which includes a phenyl and trifluoromethyl group, allows it to participate in various chemical reactions, facilitating the creation of new compounds with specific therapeutic or industrial applications.

InChI:InChI=1/C14H11F3O2S/c1-2-19-13(18)11-8-10(9-6-4-3-5-7-9)12(20-11)14(15,16)17/h3-8H,2H2,1H3

Upstream product

• 119197-25-0 (Z)-2-phenyl-3-chloro-4,4,4-trifluoro-but-2-en-1-al 
• 623-51-8 ethyl 2-sulfanylacetate 
• 350-92-5 1,1,1-Trifluoro-3-phenylpropan-2-one 
• 119197-24-9 3-chloro-4,4,4-trifluoro-2-phenyl-but-2-enal 

Downstream Products

• 917873-20-2 3-(4-hydroxy-3,5-dimethyl-phenyl)-1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-propan-1-one 
• 569685-49-0 3-[(4-carbomethoxy)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 569685-50-3 3-[(4-hydroxymethyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 569685-42-3 3-[(4-formyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 569685-43-4 4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzaldehyde 
• 208108-75-2 5-trifluoromethyl-4-phenyl-thiophene-2-carboxylic acid chloride 
• 256488-46-7 2-hydroxymethyl-4-phenyl-5-trifluoromethylthiophene 
• 208108-76-3 (4-phenyl-5-trifluoromethyl)thiophene-2-carboxylic acid 

Relevant academic research and scientific papers

NOVEL THIOPHENE DERIVATIVES

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

Moderately potent, selective S1P1 receptor agonists identified from high-throughput screening have been adapted into lipophilic tails for a class of orally bioavailable amino acid-based S1P1 agonists represented by 7. Many of the new

Microbicidal agents based on thiophene-2-carboxylic acid derivatives

PCT No. PCT/EP97/06368 Sec. 371 Date May 26, 1999 Sec. 102(e) Date May 26, 1999 PCT Filed Nov. 14, 1997 PCT Pub. No. WO98/23605 PCT Pub. Date Jun. 4, 1998Novel microbicidal compositions based on thiophene-2-carboxylic acid derivatives, some of which are k

Reactivity of trifluoromethyl enones in Michael additions

A synthesis of trifluoromethyl enones 3 is described. 3a is transformed into the vinyl sulfide 11E,Z.In basic conditions, 11 produces th unusual dihydro-thiophene 10, whose formation from the episulfide 12 is discussed.The natural bonding orbital procedur