167280-05-9

Basic information

• Product Name: 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide
• Synonyms: 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide
• CAS NO: 167280-05-9
• Molecular Weight: 293.43
• Mol File: 167280-05-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide(167280-05-9)
• EPA Substance Registry System: 2-Cyclohexyl-4,4-dimethyl-3-phenyl-[1,2]thiazetidine 1,1-dioxide(167280-05-9)

Safety Data

• Hazardous Substances Data: 167280-05-9(Hazardous Substances Data)

Upstream product

• 97273-03-5 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid 
• 74-88-4 methyl iodide 

Downstream Products

• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 6330-39-8 bis-(propane-2-sulfonyl)-methane 
• 2211-66-7 N-phenyl(methylidene)cyclohexanamine 
• 4238-09-9 phenyl isopropyl sulfone 
• 13719-46-5 (E)-N-cyclohexyl-2-phenylethenesulfonamide 
• 97273-03-5 2-Cyclohexyl-3-phenyl-1,2-thiazetidin-1,1-dioxid 
• 176696-63-2 (E)-2-Phenyl-1-trimethylsilanyl-ethenesulfonic acid cyclohexylamide 
• 208395-41-9 2-Cyclohexyl-3-phenyl-4,4-bis-trimethylsilanyl-[1,2]thiazetidine 1,1-dioxide 

Relevant articles and documents

Reactions of 1,2-thiazetidine 1,1-dioxides with organometallics: β- elimination and N-S bond cleavage

Reactions of 4-nonsubstituted β-sultams 1 with methyllithium gave only (E)-vinylsulfonamides 2, whereas 2-aminoethyl sulfones 3 were obtained as minor products by use of methylmagnesium bromide. Reactions of 4- monosubstituted β-sultams 6 with organolithiums gave (E)-vinylsulfonamides 7 stereoselectively regardless of the configuration of 3- and 4-substituents. Treatment of 4,4-dimethyl-β-sultam 8a with methylmagnesium bromide and methyllithium provided 2-aminoethyl sulfone 9 and bis-sulfone 10, respectively, and isopropyl phenyl sulfone 11 was obtained by use of phenyllithium or phenylmagnesium bromide.