16732-60-8 Usage
General Description
4-Nitro-1H-indole-2-carboxylic acid is a chemical compound that belongs to the indole carboxylic acid family. It is a nitro-substituted derivative of 1H-indole-2-carboxylic acid, and is known for its yellow crystalline appearance. 4-Nitro-1H-indole-2- carboxylic acid is used in various research and industrial applications, including organic synthesis, pharmaceuticals, and agrochemicals. It has potential medicinal properties and has been studied for its antitumor and antimicrobial activities. 4-Nitro-1H-indole-2-carboxylic acid is considered an important building block in the synthesis of biologically active compounds. Its structure consists of a nitro group (-NO2) attached to the 4th position of the indole ring and a carboxylic acid group (-COOH) attached to the 2nd position, making it a versatile molecule for chemical manipulation and further derivatization.
Check Digit Verification of cas no
The CAS Registry Mumber 16732-60-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,3 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16732-60:
(7*1)+(6*6)+(5*7)+(4*3)+(3*2)+(2*6)+(1*0)=108
108 % 10 = 8
So 16732-60-8 is a valid CAS Registry Number.
16732-60-8Relevant articles and documents
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Parmerter et al.
, p. 4621 (1958)
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MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
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, (2012/12/14)
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Modulators of ATP-binding cassette transporters
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Page/Page column 139, (2008/06/13)
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.