16736-09-7

Upstream product

• 1007-32-5 benzyl ethyl ketone 
• 100-52-7 benzaldehyde 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 501-65-5 diphenyl acetylene 

Downstream Products

• 181695-85-2 4-(3-ethyl-5-phenylisoxazol-4-yl)benzenesulfonamide 
• 181696-91-3 4,5-diphenyl-3-ethylisoxazole 
• 16737-10-3 1,2-diphenyl-1-pentene-3-one oxime 

Relevant academic research and scientific papers

RHODIUM CARBONYL-CATALYZED CROSS-HYDROCARBONYLATION OF ACETYLENES AND ETHYLENE. SYNTHESIS OF α,β-UNSATURATED KETONES

The cross-hydrocarbonylation of acetylenes and ethylene with CO and H2 in the presence of Rh4(CO)12 gave α,β-unsaturated ethyl ketones regio- and stereoselectively.

Substituted isoxazoles for the treatment of inflammation

A class of substituted isoxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula (III) wherein R7 is selected from hydroxyl, lower alkyl, carboxyl, halo, lower carboxylalkyl, lower alkoxycarbonylalkyl, lower alkoxyalkyl, lower carboxyalkoxyalkyl, lower haloalkyl, lower haloalkylsulfonyloxy, lower hydroxyalkyl, lower aryl (hydroxylalkyl), lower carboxyaryloxyalkyl, lower alkoxycarbonylaryloxyalkyl, lower cycloalkyl, lower cycloalkylalkyl, and lower aralkyl; and wherein R8 is one or more radicals independently selected from hydrido, lower alkylsulfinyl, lower alkyl, cyano, carboxyl, lower alkoxycarbonyl, lower haloalkyl, hydroxyl, lower hydroxyalkyl, lower haloalkoxy, amino, lower alkylamino, lower arylamino, lower aminoalkyl, nitro, halo, lower alkoxy, aminosulfonyl, and lower alkylthio; or a pharmaceutically-acceptable salt thereof.