16761-04-9

Basic information

• Product Name: 5-dimethylamino-2-nitrosophenol
• Synonyms: 5-dimethylamino-2-nitrosophenol;2-Nitroso-5-(dimethylamino)phenol;3-(Dimethylamino)-6-nitrosophenol;5-(N,N-Dimethylamino)-2-nitrosophenol
• CAS NO: 16761-04-9
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• EINECS: 240-819-2
• Mol File: 16761-04-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 337.6°Cat760mmHg
• Flash Point: 158°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 5.29E-05mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 5-dimethylamino-2-nitrosophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-dimethylamino-2-nitrosophenol(16761-04-9)
• EPA Substance Registry System: 5-dimethylamino-2-nitrosophenol(16761-04-9)

Safety Data

• Hazardous Substances Data: 16761-04-9(Hazardous Substances Data)

Usage

General Description

5-Dimethylamino-2-nitrosophenol is a chemical compound with the molecular formula C8H10N2O2. It has a yellow to orange color and is commonly used as a pH indicator with a transition range between pH 9.2 and 10.6. 5-dimethylamino-2-nitrosophenol is often used in analytical chemistry and medical diagnostics to determine the pH level of a solution. Additionally, 5-dimethylamino-2-nitrosophenol is a nitrosamine, which is a type of organic compound that has been linked to potential health risks, including being a potential carcinogen. Therefore, care should be taken when working with this chemical including wearing appropriate personal protective equipment and following safe handling procedures.

InChI:InChI=1/C8H10N2O2/c1-10(2)6-3-4-7(9-12)8(11)5-6/h3-5,11H,1-2H3

Upstream product

• 7647-01-0 hydrogenchloride 
• 99-07-0 3-Dimethylaminophenol 

Downstream Products

• 52886-80-3 N-(7-(dimethylamino)-3H-phenoxazin-3-ylidene)-N-methylmethanaminium 
• 105074-46-2 7-Dimethylamino-3-(3-acetoxy-4-nitrostyryl)-1,4-benzoxazin-2-one 
• 105074-45-1 7-Dimethylamino-3-(3-benzyloxystyryl)-1,4-benzoxazin-2-one 
• 105074-42-8 7-Dimethylamino-3-(3-nitrostyryl)-1,4-benzoxazin-2-one 
• 105074-41-7 7-dimethylamino-3-(p-nitrostyryl)-2H-1,4-benzoxazin-2-one 
• 105074-40-6 7-dimethylamino-3-(p-(dimethylamino)styryl)-2H-1,4-benzoxazin-2-one 
• 105074-49-5 4-{(1E)-2-(7-(dimethylamino)-2-oxo-2H-benzo-[b][1,4]oxazin-3-yl)vinyl}benzaldehyde 
• 105074-39-3 7-Dimethylamino-3-styryl-1,4-benzoxazin-2-one 
• 92510-35-5 3-Benzyl-7-dimethylamino-1,4-benzoxazin-2-one 
• 92510-34-4 7-dimethylamino-3-phenyl-2H-1,4-benzoxazin-2-one 
• 14703-85-6 2-amino-5-(dimethylamino)phenol dihydrochloride 
• 15103-39-6 2-amino-5-(dimethylamino)phenol 

Relevant articles and documents

Intraduplex DNA-mediated electrochemistry of covalently tethered redox-active reporters

Intraduplex DNA-mediated reduction is established as a general mechanism for the reduction of distally bound stacked redox-active species covalently tethered to DNA through flexible alkane linkages. Methylene Blue (MB), Nile Blue (NB), and Anthraquinone (AQ) were covalently tethered to DNA with three different covalent linkages. Using these reporters DNA electrochemistry was shown to be both DNA-mediated and intra-, rather than inter-, duplex. Significantly, the charge transport pathway occurring through the DNA π-stack is established by using an intervening AC mismatch to break this path. The fact that the DNA-mediated reduction of MB occurs primarily via intraduplex intercalation is established through varying the proximity and integrity of the neighboring duplex DNA.

NEAR-INFRARED NERVE-SPARING FLUOROPHORES

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Quinazoline fluorescent probe and preparation method and application thereof

The invention belongs to the technical field of biomedicine and particularly relates to a quinazoline fluorescent probe and a preparation method and application thereof. The chemical formula of the quinazoline fluorescent probe is shown in the formula I, wherein R is selected from H or Cl; R is selected from fluorescent molecules; and n is an integer from 2 to 8. Through the quinazoline fluorescent probe and the preparation method and application thereof, the interference of autofluorescence of an organism can be eliminated, and the TSPO content in the organism can be detected efficiently and accurately.