16768-98-2Relevant articles and documents
CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS
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Page/Page column 27, (2015/03/13)
The invention relates to compounds for increasing GPR40 recetpor activity and application thereof. These compounds include of a compound of Formula (I), pharmaceutically acceptable salts thereof, solvates thereof, isomers thereof, or produgs of the compou
Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 5-hydroxy-1H-indole-3-carboxylates
Zhao, Chunshen,Zhao, Yanfang,Chai, Huifang,Gong, Ping
, p. 2552 - 2558 (2007/10/03)
A series of ethyl 5-hydroxy-1H-indole-3-carboxylates 6A-10 T were synthesized and evaluated for their anti-hepatitis B virus (HBV) activities in 2.2.15 cells. The IC50 and selective index of inhibition on replication of HB
BICYCLIC DERIVATIVES AS PPAR MODULATORS
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Page/Page column 74, (2008/06/13)
The present invention is directed to compounds represented by the following structural formula, Formula (I), and stereoisomers, pharmaceutically acceptable salts, solvates and hydrates thereof, wherein: (a) R2 is selected from the group consisting of C0-C8 alkyl and C1-4- heteroalkyl; (b) X is selected from the group consisting of a single bond, O, S, S(O)2 and N; (c) U is an aliphatic linker wherein one carbon atom of the aliphatic linker is optionally replaced with O, NH or S, and wherein such aliphatic linker is optionally substituted with from one to four substituents each independently selected from R30; (d) Y is selected from the group consisting of C, O, S, NH and a single bond; and (e) E is C(R3)(R4)A or A.