16771-90-7

Usage

Uses

Used in Recreational Drug Industry:
1-(1-methyl-2-phenylethyl)-4-piperidone is used as a recreational drug for its stimulating and euphoric effects. As a norepinephrine-dopamine reuptake inhibitor, it increases the levels of these neurotransmitters in the brain, leading to the desired psychological outcomes. However, it is important to note that the use of MDPK as a recreational drug can have potential health risks and legal implications.

Upstream product

• 26822-37-7 N,N-dimethyl-4-oxopiperidinium iodide 
• 51-64-9 (+)-amphetamine 

Relevant academic research and scientific papers

PESTICIDAL SUBSTITUTED PIPERIDINES

The invention relates to the use of piperidine derivatives encompassed from the general formula (I) for the control of pests, including arthropods and helminths, and a method for the control of pests.

STERIC CONTROL OF THE ASYMMETRIC SYNTHESIS OF N-SUBSTITUTED 2-METHYL-4-PIPERIDONES

Transmission of the iodomethylate of 1,2-dimethyl-4-piperidone by (S)-sec-butylamine gives 1-(S-sec-butyl)-2S-methyl-4-piperidone in 33percent optical yield while transamination by (S)-1-methyl-2-phenylethylamine gives a 1:1 diastereomeric mixture of 1-(1-methyl-2-phenylethyl)-2-methyl-4-piperidone.The decrease in the optical yield is related to the facile opening of the piperidone ring at the C-N bond with subsequent recyclization.The 13C NMR data indicate that all the diastereomers of the 4-piperidones obtained are in the chair conformation with predominantly equatorial orientation of the methyl group at C(2).The chi ral optical properties were studied and the absolution configurations of the 4-piperidones were established.