16775-67-0

Basic information

• Product Name: 1,4-Dithiaspiro(4,11)-hexadecane
• Synonyms: 1,4-Dithiaspiro(4,11)-hexadecane;Cyclododecanone (ethane-1,2-diyl)dithioacetal
• CAS NO: 16775-67-0
• Molecular Formula: C₁₄H₂₆S₂
• Molecular Weight: 258.48624
• Mol File: 16775-67-0.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-Dithiaspiro(4,11)-hexadecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dithiaspiro(4,11)-hexadecane(16775-67-0)
• EPA Substance Registry System: 1,4-Dithiaspiro(4,11)-hexadecane(16775-67-0)

Safety Data

• Hazardous Substances Data: 16775-67-0(Hazardous Substances Data)

Usage

Type of compound

Dithia crown ether

Structural feature

Spiro backbone

Usage

Phase transfer catalyst in organic synthesis

Physical state

Colorless liquid

Boiling point

High

Solubility

Soluble in organic solvents (e.g., acetone, dichloromethane)

Complex formation

Stable complexes with metal cations

Applications

Chemical reactions, extraction and separation of metal ions, catalysis, pharmaceuticals, and materials science

Safety precautions

Appropriate safety measures should be taken due to potential health hazards (not thoroughly studied)

Upstream product

• 68081-20-9 1-t-butyldimethylsilyloxy-cyclododec-1-ene 
• 540-63-6 ethane-1,2-dithiol 
• 294-62-2 cyclododecane 
• 70015-94-0 1,4-oxathiaspiro<4.11>hexadecane 
• 830-13-7 cyclododecanone 

Downstream Products

• 27415-48-1 difluorocyclododecane 
• 7447-11-2 cyclododecyl mercaptane 
• 830-13-7 cyclododecanone 

Relevant articles and documents

Alicyclic ring structure: Conformational influence of the CF2 group in cyclododecanes

Getting out of the way: In fluorinated cyclododecane structures the CF 2 group locates only at corner positions (see picture). This relaxes 1,4-H,H transannular interactions as a result of C-CF2-C angle widening. Misplaced CF2 groups lead to significant ring distortion. It follows that strategic incorporation of CF2 groups has potential as a design feature to introduce order and polarity into organic hydrocarbon structures. Copyright

gem-Difluorination vs 1,3-Dithiolane-Dihydro-1,4-dithiin Rearrangement. The Role of Benzylic Carbons

1,3-Dithiolanes bearing a phenyl or substituted aromatic group and a methyl (or methylene) group attached to C-2 cannot be gem-difluorinated with 1,3-dibromo-5,5-dimethylhydantoin (DBH) (or NBS) + HF/pyridine because a rapid 1,3-dithiolane-dihydro-1,4-dit

Selective Transdithioacetalization of Acetals, Ketals, Oxathioacetals and Oxathioketals Catalyzed by Envirocat EPZ10 R

Envirocat EPZ10R has been found to be a remarkable reusable heterogeneous catalyst for selective transdithioacetalization of acetals, ketals, oxathioacetals and oxathioketals with HSCH2CH2SH and HSCH2CH2/s

A simple and efficient heterogeneous procedure for thioacetalization of aldehydes and ketones

A new procedure for the protection of aldehydes and ketones as thioacetals promoted by catalytic amount of p-toluene-sulfonic acid and silica gel has been developed. This procedure offers versatility, short reaction time, excellent yield, good selectivity