27415-48-1Relevant academic research and scientific papers
gem-Difluorination of 1,3-dithiolanes with the hexafluoropropene-diethylamine reagent and N-iodosuccinimide or 1,3-dibromo-5,5-dimethylhydantoin
Shimizu, Makoto,Maeda, Takashi,Fujisawa, Tamotsu
, p. 9 - 12 (1995)
gem-Difluoro compounds are readily prepared from 1,3-dithiolanes in good yield on treatment with hexafluoropropene-diethylamine/1,3-dibromo-5,5-dimethylhydantoin or /N-iodosuccinimide/water. - Keywords: gem-Difluorination; 1,3-Dithiolanes; NMR spectroscop
Alicyclic ring structure: Conformational influence of the CF2 group in cyclododecanes
Skibinski, MacIej,Wang, Yi,Slawin, Alexandra M. Z.,Lebl, Tomas,Kirsch, Peer,O'Hagan, David
supporting information; experimental part, p. 10581 - 10584 (2012/01/04)
Getting out of the way: In fluorinated cyclododecane structures the CF 2 group locates only at corner positions (see picture). This relaxes 1,4-H,H transannular interactions as a result of C-CF2-C angle widening. Misplaced CF2 groups lead to significant ring distortion. It follows that strategic incorporation of CF2 groups has potential as a design feature to introduce order and polarity into organic hydrocarbon structures. Copyright
Anodic gem-Difluorination of Dithioacetals
Yoshiyama, Tomonori,Fuchigami, Toshio
, p. 1995 - 1998 (2007/10/02)
Anodic desulfurization of dithioacetals of ketones in the presence of Et3N*3HF provided the corresponding gem-difluorocompounds while dithioacetals of aromatic and aliphatic aldehydes gave gem-difluorothioethers and monofluoro thioether, respectively.
gem-Difluoro Compounds: A Convenient Preparation from Ketones and Aldehydes by Halogen Fluoride Treatment of 1,3-Dithiolanes
Sondej, Susan C.,Katzenellenbogen, John A.
, p. 3508 - 3513 (2007/10/02)
gem-Difluoro compounds can be prepared from ketones and aldehydes by formation of the corresponding 1,3-dithiolanes, followed by reaction with 1,3-dibromo-5,5-dimethylhydantoin and pyridinium poly(hydrogenfluoride) (HF-pyridine) in methylene chloride.The
