27415-48-1

Basic information

• Product Name: 1,1-Difluorocyclododecane
• Synonyms: 1,1-Difluorocyclododecane
• CAS NO: 27415-48-1
• Molecular Formula: C12H22F2
• Molecular Weight: 204.3
• Mol File: 27415-48-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1-Difluorocyclododecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Difluorocyclododecane(27415-48-1)
• EPA Substance Registry System: 1,1-Difluorocyclododecane(27415-48-1)

Safety Data

• Hazardous Substances Data: 27415-48-1(Hazardous Substances Data)

Usage

Class

Cyclododecane derivatives

Structure

Cyclic compound with a 12-carbon backbone and two fluorine atoms attached to the first carbon atom

Main Uses

Component in the manufacturing of specialty chemicals
Building block for the synthesis of various organic compounds

Applications

Fluorinated polymers
Surfactants

Stability

High stability

Reactivity

Low reactivity

Industrial Importance

Valuable intermediate in the production of a wide range of industrial and consumer products

Environmental Consideration

Proper handling and disposal required to minimize environmental impact due to its fluoro-substituted structure

Upstream product

• 830-13-7 cyclododecanone 
• 16775-67-0 1,4-dithiaspiro<4.11>hexadecane 
• 85895-36-9 1,1-bis(phenylthio)cyclododecanone 
• 294-62-2 cyclododecane 

Relevant articles and documents

gem-Difluorination of 1,3-dithiolanes with the hexafluoropropene-diethylamine reagent and N-iodosuccinimide or 1,3-dibromo-5,5-dimethylhydantoin

gem-Difluoro compounds are readily prepared from 1,3-dithiolanes in good yield on treatment with hexafluoropropene-diethylamine/1,3-dibromo-5,5-dimethylhydantoin or /N-iodosuccinimide/water. - Keywords: gem-Difluorination; 1,3-Dithiolanes; NMR spectroscop

Alicyclic ring structure: Conformational influence of the CF2 group in cyclododecanes

Getting out of the way: In fluorinated cyclododecane structures the CF 2 group locates only at corner positions (see picture). This relaxes 1,4-H,H transannular interactions as a result of C-CF2-C angle widening. Misplaced CF2 groups lead to significant ring distortion. It follows that strategic incorporation of CF2 groups has potential as a design feature to introduce order and polarity into organic hydrocarbon structures. Copyright

gem-Difluoro Compounds: A Convenient Preparation from Ketones and Aldehydes by Halogen Fluoride Treatment of 1,3-Dithiolanes

gem-Difluoro compounds can be prepared from ketones and aldehydes by formation of the corresponding 1,3-dithiolanes, followed by reaction with 1,3-dibromo-5,5-dimethylhydantoin and pyridinium poly(hydrogenfluoride) (HF-pyridine) in methylene chloride.The