167755-85-3Relevant academic research and scientific papers
Ligand interactions with E-selectin. Identification of a new binding site for recognition of N-acyl aromatic glucosamine substituents of sialyl Lewis X
Ramphal, John Y.,Hiroshige, Mariann,Lou, Boliang,Gaudino, John J.,Hayashi, Masaji,Chen, Shiow Meei,Chiang, Lin C.,Gaeta, Federico C. A.,DeFrees, Shawn A.
, p. 1357 - 1360 (1996)
Several N-acylglucosamine derivatives of sialyl Lewis X (1-3) were prepared using a combined chemical enzymatic approach and evaluated as an inhibitor of E-selectin-mediated cellular adhesion. Compounds with aromatic functionality, 1 and 2, were found to
