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Ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is a chemical compound that belongs to the class of ethyl esters. It is characterized by its potential biological activity and is primarily utilized as a pharmaceutical intermediate in the synthesis of various drugs. ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride serves as a precursor for the production of pharmaceuticals, playing a crucial role in the development of new drugs targeting a range of diseases. Due to its hydrochloride salt form, it requires careful handling to avoid potential health hazards.

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  • 167887-35-6 Structure
  • Basic information

    1. Product Name: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride
    2. Synonyms: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride
    3. CAS NO:167887-35-6
    4. Molecular Formula: C12H18ClNO3
    5. Molecular Weight: 259.72922
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 167887-35-6.mol
  • Chemical Properties

    1. Melting Point: 133-137 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(167887-35-6)
    11. EPA Substance Registry System: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(167887-35-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 167887-35-6(Hazardous Substances Data)

167887-35-6 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs. It is valued for its role in the development of new pharmaceuticals, contributing to the advancement of treatments for a variety of diseases.
Used in Drug Development:
In the field of drug development, ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is employed as a precursor in the production of pharmaceuticals. Its potential biological activity makes it a significant component in the creation of innovative medications designed to address specific health conditions.
Used in Chemical Research:
Ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is also utilized in chemical research, where it aids in the exploration of new chemical pathways and the discovery of novel compounds with potential therapeutic applications. Its unique structure and properties make it a valuable subject for scientific investigation and experimentation.

Check Digit Verification of cas no

The CAS Registry Mumber 167887-35-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,8,8 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 167887-35:
(8*1)+(7*6)+(6*7)+(5*8)+(4*8)+(3*7)+(2*3)+(1*5)=196
196 % 10 = 6
So 167887-35-6 is a valid CAS Registry Number.

167887-35-6Downstream Products

167887-35-6Relevant articles and documents

Organosilicon synthesis of isocyanates: III. Synthesis of aliphatic, carbocyclic, aromatic, and alkylaromatic isocyanatocatboxylic acid esters

Lebedev,Lebedeva,Sheludyakov,Ovcharuk,Kovaleva,Ustinova

, p. 1069 - 1080 (2008/02/05)

A series of aminoacid esters was prepared by treating the aminoacid suspensions in ethanol with thionyl chloride. Best conversion of aminoacid esters to corresponding isocyanates was achieved in the case of aromatic and carbocyclic aminoesters by phosgeneation of their N-silyl derivatives, and in the case of aliphatic and alkylaromatic aminoesters by phosgeneation of O-silyl or N,O-bissilylurethanes on their basis. In the last case additional step of esterification of the by-products isocyanatoalkylcarboxylic acid chlorides is required after phosgeneation. Unusual generation of cynnamates and intramolecular N→O-migration of trimethylsilyl group in the solutions of silylated alkylaromatic β-aminoacid esters were found. Pleiades Publishing, Inc., 2006.

New access to racemic β3-amino acids

Nejman, Micha?,?liwińska, Anna,Zwierzak, Andrzej

, p. 8536 - 8541 (2007/10/03)

A general simple procedure having the potential for large scale preparations of racemic β3-amino acids has been developed. The procedure involves base-catalyzed Michael-type addition of sodium diethyl malonate to N-Boc-α-amidoalkyl-p-tolyl sulfones in tetrahydrofuran. Hydrolysis of the adducts by refluxing with 6 M aqueous hydrochloric acid affords β3-amino acid hydrochlorides in high yield and excellent purity.

Aromatic β-amino acids as Asp-Phg mimics in LDV derived VLA-4 antagonists

Wehner, Volkmar,Blum, Horst,Kurz, Michael,Stilz, Hans Ulrich

, p. 2023 - 2036 (2007/10/03)

Aromatic β-amino acid esters 2a-h were prepared in racemic and enantiomerically pure form by the Radionow reaction or based on the method described by Davis and used as mimics of the Asp-Phg C-terminus in LDV derived VLA-4 antagonists. As a promising β-am

Bispiperidines as antithrombotic agents

-

, (2008/06/13)

Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents

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