167887-35-6

Basic information

• Product Name: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride
• Synonyms: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride
• CAS NO: 167887-35-6
• Molecular Formula: C12H18ClNO3
• Molecular Weight: 259.72922
• Mol File: 167887-35-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 133-137 °C
• Appearance: /
• CAS DataBase Reference: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(167887-35-6)
• EPA Substance Registry System: ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride(167887-35-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 167887-35-6(Hazardous Substances Data)

Usage

General Description

Ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is a chemical compound that belongs to the class of ethyl esters. It is commonly used as a pharmaceutical intermediate and in the synthesis of various drugs, mainly as a precursor for the production of pharmaceuticals. ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride has potential biological activity and is used in the development of new drugs targeting various diseases. It is important to handle this chemical with care, as it is a hydrochloride salt and can pose potential health hazards if not managed properly. Overall, ethyl 3-amino-3-(4-methoxyphenyl)propanoate hydrochloride is a significant chemical compound with pharmaceutical and biological applications.

Upstream product

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Relevant articles and documents

Organosilicon synthesis of isocyanates: III. Synthesis of aliphatic, carbocyclic, aromatic, and alkylaromatic isocyanatocatboxylic acid esters

A series of aminoacid esters was prepared by treating the aminoacid suspensions in ethanol with thionyl chloride. Best conversion of aminoacid esters to corresponding isocyanates was achieved in the case of aromatic and carbocyclic aminoesters by phosgeneation of their N-silyl derivatives, and in the case of aliphatic and alkylaromatic aminoesters by phosgeneation of O-silyl or N,O-bissilylurethanes on their basis. In the last case additional step of esterification of the by-products isocyanatoalkylcarboxylic acid chlorides is required after phosgeneation. Unusual generation of cynnamates and intramolecular N→O-migration of trimethylsilyl group in the solutions of silylated alkylaromatic β-aminoacid esters were found. Pleiades Publishing, Inc., 2006.

Aromatic β-amino acids as Asp-Phg mimics in LDV derived VLA-4 antagonists

Aromatic β-amino acid esters 2a-h were prepared in racemic and enantiomerically pure form by the Radionow reaction or based on the method described by Davis and used as mimics of the Asp-Phg C-terminus in LDV derived VLA-4 antagonists. As a promising β-am