167887-40-3

Upstream product

• 54503-20-7 methyl 3-amino-3-(3,4-dimethoxyphenyl)propionate 
• 696641-65-3 methyl (S)-3-amino-3-(3,4-dimethoxyphenyl)propionate N-acetyl-D-phenylalanine salt 
• 5396-64-5 methyl (E)-3-(3,4-dimethoxyphenyl)acrylate 

Downstream Products

• 221664-07-9 (S)-N-<1-(3,4-dimethoxyphenyl)-2-methoxycarbonylethyl>glutarimide 
• 233274-67-4 (S)-3-(2-Bromo-acetylamino)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester 
• 905718-74-3 3-tert-butoxycarbonylamino-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester 
• 696641-73-3 (S)-3-amino-3-(3,4-dimethoxyphenyl)propanoic acid 
• 696641-65-3 methyl (S)-3-amino-3-(3,4-dimethoxyphenyl)propionate N-acetyl-D-phenylalanine salt 
• 1005325-86-9 C₂₀H₂₃NO₆ 
• 167886-80-8 (S)-CC-1104 
• 221664-06-8 6-ethoxy-N-<1-(3,4-dimethoxyphenyl)-2-methoxycarbonylethyl>piperidin-2-one 
• 233274-69-6 3-(3,4-dimethoxy-phenyl)-3-[2-((3-methoxy-propyl)-{[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-propionic acid methyl ester 
• 671225-75-5 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(4-methoxy-butylamino)-acetylamino]-propionic acid methyl ester 
• 233274-68-5 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(3-methoxy-propylamino)-acetylamino]-propionic acid methyl ester 
• 671225-43-7 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(3-methyl-butylamino)-acetylamino]-propionic acid methyl ester 
• 386285-40-1 (S)-4-(3,4-dimethoxyphenyl)-2-oxo-3,4,6,7,8,9-hexahydro-2H-quinolizine-1-carboxylic acid ethyl ester 
• 386285-44-5 (2R,4S,9aS)-2-hydroxy-4-(3,4-dimethoxyphenyl)-decahydroquinolizidine 

Relevant academic research and scientific papers

Efficient entry to polysubstituted pyrrolizidines, indolizidines and quinolizidines via a sequential reaction process

A sequential SN2-Michael addition-Michael addition reaction process between ω-iodo-α,β-alkynoates and δ- or γ-amino α,β-unsaturated esters is developed, which affords polysubstituted pyrrolizidines, indolizidines or quinolizidines in good yield

METHODS OF USING AND COMPOSITIONS COMPRISING (+)-3-(3,4-DIMETHOXY-PHENYL)-3-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONAMIDE

Enantiomerically pure (+)-3 -(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide, and prodrugs, metabolites, polymorphs, salts, solvates (e.g., hydrates), and clathrates thereof are discussed. Methods of treating and/or preventing vari

Enantioselective acylation of β-aminoesters using penicillin G acylase in organic solvents

The resolution of racemic β-aminoesters has been achieved through selective acylation catalyzed by Penicillin G Acylase (ChiroCLEC(TM)-EC). The method has been optimized using three different phenylacetyl donors, and the effect of solvents on the rate of reaction is described. The efficiency of our method is illustrated by the synthesis of five different β-aminoesters with high enantiomeric purities.

Asymmetric synthesis of quinolizidine alkaloids (-)-lasubine I, (-)- lasubine II and (+)-subcosine II

The enantioselective synthesis of (-)-lasubine I 1 and the first asymmetric synthesis of (-)-lasubine II 2 and (+)-subcosine II 3 is described. The key step is the intramolecular cyclization of N-acyliminium ion 4 which is derived from (S)-aminoester 6.