167887-40-3

Basic information

• Product Name: methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate
• Synonyms: methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate
• CAS NO: 167887-40-3
• Molecular Weight: 239.271
• Mol File: 167887-40-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate(167887-40-3)
• EPA Substance Registry System: methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate(167887-40-3)

Safety Data

• Hazardous Substances Data: 167887-40-3(Hazardous Substances Data)

Upstream product

• 54503-20-7 methyl 3-amino-3-(3,4-dimethoxyphenyl)propionate 
• 696641-65-3 methyl (S)-3-amino-3-(3,4-dimethoxyphenyl)propionate N-acetyl-D-phenylalanine salt 
• 5396-64-5 methyl (E)-3-(3,4-dimethoxyphenyl)acrylate 

Downstream Products

• 905718-74-3 3-tert-butoxycarbonylamino-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester 
• 696641-73-3 (S)-3-amino-3-(3,4-dimethoxyphenyl)propanoic acid 
• 696641-65-3 methyl (S)-3-amino-3-(3,4-dimethoxyphenyl)propionate N-acetyl-D-phenylalanine salt 
• 1005325-86-9 C₂₀H₂₃NO₆ 
• 167886-80-8 (S)-CC-1104 
• 221664-06-8 6-ethoxy-N-<1-(3,4-dimethoxyphenyl)-2-methoxycarbonylethyl>piperidin-2-one 
• 233274-69-6 3-(3,4-dimethoxy-phenyl)-3-[2-((3-methoxy-propyl)-{[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-propionic acid methyl ester 
• 671225-75-5 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(4-methoxy-butylamino)-acetylamino]-propionic acid methyl ester 
• 233274-68-5 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(3-methoxy-propylamino)-acetylamino]-propionic acid methyl ester 
• 671225-43-7 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-(3-methyl-butylamino)-acetylamino]-propionic acid methyl ester 
• 386285-40-1 (S)-4-(3,4-dimethoxyphenyl)-2-oxo-3,4,6,7,8,9-hexahydro-2H-quinolizine-1-carboxylic acid ethyl ester 
• 386285-44-5 (2R,4S,9aS)-2-hydroxy-4-(3,4-dimethoxyphenyl)-decahydroquinolizidine 
• 386285-43-4 (S)-4-(3,4-Dimethoxy-phenyl)-3,4,6,7,8,9-hexahydro-quinolizin-2-one 
• 68681-73-2 (-)-(2S,4S,9aS)-2-hydroxy-4-(3,4-dimethoxyphenyl)-decahydroquinolizidine 

Relevant articles and documents

Efficient entry to polysubstituted pyrrolizidines, indolizidines and quinolizidines via a sequential reaction process

A sequential SN2-Michael addition-Michael addition reaction process between ω-iodo-α,β-alkynoates and δ- or γ-amino α,β-unsaturated esters is developed, which affords polysubstituted pyrrolizidines, indolizidines or quinolizidines in good yield

Enantioselective acylation of β-aminoesters using penicillin G acylase in organic solvents

The resolution of racemic β-aminoesters has been achieved through selective acylation catalyzed by Penicillin G Acylase (ChiroCLEC(TM)-EC). The method has been optimized using three different phenylacetyl donors, and the effect of solvents on the rate of reaction is described. The efficiency of our method is illustrated by the synthesis of five different β-aminoesters with high enantiomeric purities.