54503-20-7

Usage

InChI:InChI=1/C12H17NO4/c1-15-10-5-4-8(6-11(10)16-2)9(13)7-12(14)17-3/h4-6,9H,7,13H2,1-3H3/p+1/t9-/m1/s1

Upstream product

• 67-56-1 methanol 
• 34840-85-2 3-amino-3-(3,4-dimethoxyphenyl)propanoic acid 
• 75-36-5 acetyl chloride 

Downstream Products

• 1184872-14-7 tert-butyl (1-(3,4-dimethoxyphenyl)-3-hydroxypropyl)carbamate 
• 1378029-24-3 methyl 3-((tert-butoxycarbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoate 
• 1243990-42-2 C₃₁H₄₁N₃O₈ 
• 1026996-80-4 methyl 3-(3,4-dimethoxyphenyl)-3-(1-nitro-4,6-dioxo-4H-thiophene[3,4-c]pyrrole-5(6H)-yl)propionate 
• 1026995-73-2 methyl 3-(3,4-dimethoxyphenyl)-3-(4,6-dioxo-4H-thiophene[3,4-c]pyrrole-5(6H)-yl)propionate 
• 201408-35-7 3-amino-3-(3,4-dimethoxyphenyl)propan-1-ol 
• 220946-57-6 3-(3,4-Dimethoxy-phenyl)-3-phenylacetylamino-propionic acid 
• 713513-03-2 (R)-3-amino-3-(3,4-dimethoxyphenyl)propanoic acid 
• 911224-87-8 (R)-3-amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride 
• 167887-40-3 methyl (3S)-3-amino-3-(3,4-dimethoxyphenyl)propanoate 

Relevant academic research and scientific papers

CuproCleav-1, a first generation photocage for Cu+

By utilizing thioether ligands, CuproCleav-1 stabilizes Cu+ complexes in aqueous solution and releases the guest metal ion upon photolysis of the nitrobenzyl group. The photocage has an apparent Kd of 54 pM for Cu+, and metal ion release has been demonstrated using the fluorescent sensor CS1.

PYRROLINE DERIVATIVES AGAINST CELL RELEASING TUMOR NECROSIS FACTOR, PREPARATION METHODS AND USES THEREOF

Compounds represented by Formula (I) or Formula (II) against cell releasing TNFα, their pharmaceutically acceptable salts or hydrates and preparation methods and uses thereof, in which A and B represent CH2, CO, SO, or SO2; D represents S, NH, or NC1-6 alkyl; R1 represents H, or one or two same or different radical(s) selected from the group consisting of F, Cl, Br, C1-4 alkyl,OH,OC1-4 alkyl,NO2,NHC(O)C1-4 alkyl,NH2,NH(C1-4 alkyl), or N(C1-4 alkyl)2.

Immunotherapeutic imides/amides

Imide/amide ethers and alcohols are inhibitors of cytokines including tumor necrosis factor α and can be used to combat cachexia, endotoxic shock, arthritis, asthma, and retrovirus replication. A typical embodiment is 3-Phthalimido-3-(3', 4'-dimethoxyphenyl)propan-1-ol.