16790-59-3

Basic information

• Product Name: AKOS BB-9929
• Synonyms: AKOS BB-9929;CHEMBRDG-BB 4012469;acetamide, N-(4-oxotricyclo[3.3.1.1~3,7~]dec-1-yl)-
• CAS NO: 16790-59-3
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.271
• Mol File: 16790-59-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 412.1°C at 760 mmHg
• Flash Point: 178.2°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 5.31E-07mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: AKOS BB-9929(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS BB-9929(16790-59-3)
• EPA Substance Registry System: AKOS BB-9929(16790-59-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 16790-59-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17NO2/c1-7(14)13-12-4-8-2-9(5-12)11(15)10(3-8)6-12/h8-10H,2-6H2,1H3,(H,13,14)

Upstream product

• 56674-87-4 4-oxoadamantane-1-carboxylic acid 
• 75-36-5 acetyl chloride 
• 944123-99-3 tert-butyl N-(4-oxoadamantan-1-yl)carbamate 
• 20098-14-0 chemantane 
• 75-05-8 acetonitrile 

Relevant articles and documents

Synthesis and identification of an important metabolite of AKB-48 with a secondary hydroxyl group on the adamantyl ring

Studies on the metabolism of bioactive substances containing the adamantyl moiety have shown that hydroxylation is likely to occur at a tertiary carbon of adamantane. Herein, we report the synthesis and identification of one major metabolite of AKB-48, a new illicit psychoactive substance with a hydroxyl group at a secondary carbon of the adamantyl ring.

Ring-fused compound, pharmaceutical composition containing same and application of compound

The invention discloses a ring-fused compound, a preparation method thereof, pharmaceutical composition containing the compound and an application of the compound. A polycyclic compound (I) as well asan isomer, a prodrug, a stable isotopic derivative or pharmacologically acceptable salt of the compound (I) has the following structure. The polycyclic compound has good IDO1 and/or TDO2 inhibition functions, can effectively treat, relieve and/or prevent various diseases which are related with IDO1 and/or TDO2, such as cancer, virus infection, autoimmune diseases or the like.