167951-80-6

Basic information

• Product Name: 3,3,3-TRIFLUOROPROPYLENE CARBONATE
• Synonyms: 3,3,3-TRIFLUOROPROPYLENE CARBONATE;3,3,3-Trifluoroproplylene carbonate;4-trifluoroMethyl ethylence carbonate;4-Trifluoromethyl-1,3-dioxolan-2-one
• CAS NO: 167951-80-6
• Molecular Formula: C₄H₃F₃O₃
• Molecular Weight: 156.06
• Mol File: 167951-80-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 206.6°Cat760mmHg
• Flash Point: 76.8°C
• Appearance: /
• Density: 1.554g/cm³
• Vapor Pressure: 0.235mmHg at 25°C
• Refractive Index: 1.356
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,3,3-TRIFLUOROPROPYLENE CARBONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,3-TRIFLUOROPROPYLENE CARBONATE(167951-80-6)
• EPA Substance Registry System: 3,3,3-TRIFLUOROPROPYLENE CARBONATE(167951-80-6)

Safety Data

• Hazardous Substances Data: 167951-80-6(Hazardous Substances Data)

Usage

Description

3,3,3-Trifluoropropylene Carbonate is a chemical compound with the molecular formula C4H3F3O3. It is a colorless liquid with a low boiling point and high reactivity. 3,3,3-TRIFLUOROPROPYLENE CARBONATE is characterized by the presence of three fluorine atoms attached to a propylene carbonate backbone, which imparts unique properties such as increased stability, reactivity, and resistance to hydrolysis.

Uses

Used in Pharmaceutical Industry:
3,3,3-Trifluoropropylene Carbonate is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique reactivity and stability make it a valuable building block for the development of new drugs with improved properties, such as enhanced solubility, bioavailability, and stability.
Used in Polymer Industry:
In the polymer industry, 3,3,3-Trifluoropropylene Carbonate is used as a monomer for the production of fluoropolymers. These polymers exhibit excellent thermal stability, chemical resistance, and low surface energy, making them suitable for applications in coatings, adhesives, and sealants.
Used in Agrochemical Industry:
3,3,3-Trifluoropropylene Carbonate is also used as a starting material in the synthesis of agrochemicals, such as insecticides and herbicides. Its unique properties allow for the development of more effective and environmentally friendly pesticides.
Used in Preparation of 3,3,3-Trifluoropropylene Carbonate:
3,3,3-Trifluoropropylene Carbonate is used in the preparation of itself, which may seem redundant but is essential for maintaining a consistent supply of this valuable chemical compound for various industries and applications.

InChI:InChI=1/C4H3F3O3/c5-4(6,7)2-1-9-3(8)10-2/h2H,1H2

Upstream product

• 431-39-0 (rac)-3,3,3-trifluoro-1,2-propanediol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 359-41-1 1,1,1-trifluoro-2,3-epoxypropane 
• 124-38-9 carbon dioxide 
• 311-86-4 2-bromo-3,3,3-trifluoropropan-1-ol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 75-44-5 phosgene 
• 616-38-6 carbonic acid dimethyl ester 

Relevant articles and documents

3-Bromo-1,1,1-trifluoro-2-propanol assisted chemical fixation of CO2 and epoxides

3-Bromo-1,1,1-trifluoro-2-propanol (3-BTFP) in combination with n-butylammonium iodide (TBAI) was proved to be an efficient organocatalyst for chemical fixation of CO2 with various epoxides to the respective cyclic carbonates. A possible reaction mechanism was proposed wherein 3-BTFP activated epoxide through hydrogen bonding interaction. This mechanism is revealed by the results of FT-IR spectra and 1H NMR titration, and the synergetic effect functioned by 3-BTFP and TBAI ensures the reaction proceeding effectively. Herein, 3-BTFP represents a commercially available, stable and metal-free hydrogen-bonding donor for CO2 transformation, which has a potential application for the large-scale synthesis of cyclic carbonates.

Straightforward access to high-performance organometallic catalysts by fluoride activation: Proof of principle on asymmetric cyanation, asymmetric Michael addition, CO2 addition to epoxide, and reductive alkylation of amines by tetrahydrofuran

We demonstrate that well-known transition metal catalysts can be transformed into high-performance versions by the simple use of a fluoride anion source. In situ fluoride-activated catalysts are highly active catalytic species. The isolation may lead to degradation of the species or a decrease in catalytic activity. Fluoride activation of known, relatively simple catalysts resulted in the development of one of the most efficient catalytic systems for the asymmetric cyanation of aldehydes, asymmetric Michael addition, and synthesis of cyclic carbonates. Furthermore, the fluoride-assisted reductive opening of tetrahydrofuran (THF) with amines was developed. We believe that the proposed approach can find broad applications in the enhancement of known catalytic processes and in the design of new ones.

Simultaneous shaping and confinement of metal-organic polyhedra in alginate-SiO2spheres

The simultaneous shaping and confinement of Cu-based MOP in alginate-SiO2 spheres significantly enhance the mechanical strength and leaching resistance of Cu-MOP. The resulting MOP-alginate-SiO2 is shown through chemical fixation of CO2 to exhibit improved product yield over the parent Cu-MOP and Cu-alginate-SiO2. This journal is