168030-57-7Relevant academic research and scientific papers
Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes
Cox, Russell J.,Ritson, Dougal J.,Dane, Thomas A.,Berge, John,Charmant, Jonathan P. H.,Kantacha, Anob
, p. 1037 - 1039 (2005)
Conditions are reported for the facile, high-yielding coupling of acyl chlorides with terminal alkynes in a reaction involving palladium and copper iodide; the reaction is tolerant of a wide variety of acyl chlorides and terminal alkynes and provides a co
Three-component synthesis of N-boc-4-iodopyrroles and sequential one-pot alkynylation
Merkul, Eugen,Boersch, Christina,Frank, Walter,Mueller, Thomas J.J.
supporting information; experimental part, p. 2269 - 2272 (2009/09/30)
(Hetero)aryl-, alkenyl-, and selected alkyl-substituted acid chlorides can be efficiently coupled with N-Boc-protected propargylamine to produce ynones which are converted in a one-pot fashion to 2-substituted N-Boc-4-iodopyrroles. Upon addition of a furt
A new approach to the synthesis of N-protected 2- and 5-substituted 3-halopyrroles
Masquelin,Obrecht
, p. 276 - 284 (2007/10/02)
A new and efficient method for the preparation of N-protected 5- and 2-substituted 3-bromopyrroles 15 and 16 via acid-catalyzed cyclization of the corresponding acetylenic ketones 6 and acetylenic acetals 14 has been found (Scheme 3). Using this methodolo
