1681-24-9

Usage

Uses

Used in Pharmaceutical Industry:
Dibromoacetyl bromide is used as a reagent in the synthesis of various pharmaceutical compounds. Its high reactivity allows it to participate in acylation and bromination reactions, which are crucial for the production of a range of medications.
Used in Agricultural Chemical Industry:
In the agricultural sector, dibromoacetyl bromide serves as a key component in the creation of agrochemicals. Its ability to undergo diverse chemical reactions makes it an essential tool in developing effective products for crop protection and other agricultural applications.
Safety Precautions:
Due to its corrosive nature, dibromoacetyl bromide can cause severe skin and eye irritation. It is also highly flammable and can release toxic fumes when heated. Therefore, it is imperative to handle this chemical compound with extreme care, using appropriate safety measures to prevent accidents and health hazards.

InChI:InChI=1/C2HBr3O/c3-1(4)2(5)6/h1H

Upstream product

• 598-21-0 2-Bromoacetyl bromide 
• 7789-69-7 phosphorus pentabromide 
• 598-16-3 1,1,2-tribromoethylene 
• 631-64-1 dibromoacetic acid 
• 64-19-7 acetic acid 

Downstream Products

• 617-33-4 ethyl dibromoacetate 
• 29768-17-0 2,2-dibromo-N-phenylacetamide 
• 51714-50-2 2,2-Dibromo-N-(1-methyl-2-oxo-2-phenyl-ethyl)-acetamide 

Relevant academic research and scientific papers

Liquid-phase oxidation of bromovinyl compounds with molecular oxygen

Liquid-phase oxidation of bromovinyl compounds with the aim to obtain the corresponding α-bromo acids was studied.

Activated Basic Alumina Promotes a Mild, Clean and High-Yield Racemization-Free Synthesis of t-Butyl Esters from Chiral Acid Bromides and t-Butyl Alcohol

Esterification of a variety of acid bromides having even steric bulkiness with t-BuOH/activated basic alumina gave the corresponding t-butyl esters in good to excellent yields.In the case of chiral acid bromides, no racemization has been ascertained for the first time.

STEREOCHEMICAL OBSERVATIONS IN THE SYNTHESIS OF NOVEL 1,4,5,9b-TETRAHYDRO-5-PHENYL-2H-AZETOIOSQUINOLIN-2-ONE DERIVATIVES

Imine (5) reacted with Cl2CHC(O)Cl in the presence of Et3N to give β-lactams (7a) and (7b) in a 4:1 ratio.The stereochemistry of cycloadduct (7a) was confirmed by X-ray analysis.Uncyclized intermediates were identified.Reduction of dichloro β-lactam (7a) with Zn/HOAc gave mostly exo monochloride (13a), with high stereoselectivity (10:1 ratio).Reduction of a mixture of exo and endo monochlorides (13a) and (13b) with Zn/HOAc indicated that the more sterically hidered endo chlorine is preferentially attacked.Reduction of (7a) with Bu3SnH gave β-lactam (14a) as the major product.

Oxidation of halo-olefins

Process for the non-catalytic liquid phase oxidation of halo-olefins, having 2 to 7 carbon atoms, by O2 at elevated temperatures and pressures to produce oxygenated organic products having the same number of carbon atoms as the starting material.