16810-40-5Relevant articles and documents
Ligandless copper-catalyzed coupling of heteroaryl bromides with gaseous ammonia
Fantasia, Serena,Windisch, Johannes,Scalone, Michelangelo
supporting information, p. 627 - 631 (2013/04/11)
A range of different N- and S-containing heterocyclic bromides can be efficiently coupled with gaseous ammonia in the presence of copper(II) acetylacetonate [Cu(acac)2] as catalyst and in the absence of additional ligands. Unstable aminothiophenes and aminobenzothiophenes can be further reacted in situ to afford functionalized derivatives. Copyright